Your Strength. Our Knowledge and Experience.

Dr. Mahmoudieh has been a vital member of El Portal Comprehensive Cancer Centers since 2008, bringing over a decade of dedicated experience to patient care. Before joining our team, he served as the Director of the Prostate Brachytherapy Program at Kaiser Permanente in Sacramento and Roseville, demonstrating his leadership in advanced cancer treatments.

He earned his medical degree from the Albert Szent-Györgyi School of Medicine in Szeged, Hungary, in 1996. With a strong interest in treating head, neck, and breast cancers, Dr. Mahmoudieh specializes in cutting-edge techniques such as Image-Guided Radiation Therapy (IGRT) and Intensity-Modulated Radiation Therapy (IMRT). His expertise extends to treating cancers of the head and neck, lung, gastrointestinal tract, and prostate.

A committed professional, Dr. Mahmoudieh is a member of the American Society for Therapeutic Radiology and Oncology (ASTRO), reflecting his engagement with ongoing developments in cancer treatment and research. His compassionate approach and advanced skill set ensure that each patient receives personalized, state-of-the-art care.

Outside of his professional life, Dr. Mahmoudieh enjoys traveling with his son and daughter, as well as reading and playing racquetball, embracing a balanced and active lifestyle. His dedication to both his patients and his personal passions makes him a trusted partner in your journey toward health.

Dr. Elhanafy is a highly respected Associate Professor of Medical Physics and serves as the Chief Medical Physicist at El Portal Comprehensive Cancer Centers since July 2013. He earned his Ph.D. in Medical Physics from the University of Wisconsin, Madison—where he began his foundational training and completed his thesis—in 2013, building on his initial joining of the university in 1999.

 With specialized training in advanced radiation oncology techniques—such as Intensity-Modulated Radiation Therapy (IMRT), High-Dose Rate Brachytherapy (HDR), Stereotactic Radiosurgery (SRS), Total Body Irradiation (TBI), Quality Assurance, and Radiobiology—Dr. Elhanafy brings a wealth of expertise to patient care. His dedication to the field is evident through numerous published research articles, as well as awards recognizing his leadership in organizing conferences, training sessions, lectures, and workshops.

Beyond his impressive credentials, Dr. Elhanafy is deeply committed to advancing medical physics and ensuring the best possible outcomes for his patients. His compassionate approach, combined with his extensive knowledge, makes him a trusted partner in your cancer care journey.

Outside of his professional pursuits, he values spending quality time with his family, reflecting his genuine care and balance in life.

Dr. Ahuja is a distinguished, board-certified Medical Oncologist with extensive training in medical hematology. He has refined his expertise at renowned institutions such as Tata Memorial Hospital, UCLA School of Medicine, and Roswell Park, under the mentorship of esteemed hematologists including Dr. S.H. Advani, Dr. Michael Caligiuri, and Dr. M.J. Cline.

With over 25 years of experience in both hematology and oncology, Dr. Ahuja offers a deep well of knowledge and a compassionate approach to patient care at El Portal Cancer Center. His dedication to advancing the field is reflected through active membership in prestigious professional organizations, including the American Society of Hematology, the American Society of Clinical Oncology, the European Society of Medical Oncology, and the Indian Society of Medical and Pediatric Oncology.

A passionate researcher, Dr. Ahuja has contributed significantly to ongoing scientific advancements—serving on the NRG Breast Committee and the Rare Subtype Committee, and acting as Principal Investigator for the “CROWN” NCORP study. His commitment to clinical excellence and groundbreaking research underscores his dedication to improving outcomes for his patients.

Outside of his professional pursuits, Dr. Ahuja values spending quality time with his family, and enjoys hiking and traveling, embracing life outside the clinic with the same dedication he brings to his medical practice. His compassionate nature and extensive experience make him a trusted partner in your cancer care journey.

Dr. Crain is a highly experienced and board-certified Medical Oncologist and Hematologist with over 45 years of dedicated service in the medical field. Throughout his distinguished career, he has established himself as a leading expert in the diagnosis, treatment, and prevention of various cancers and blood disorders.

He earned his medical degree from the University of Illinois College of Medicine in 1977 and is actively affiliated with esteemed institutions, including Adventist Health St. Helena. Dr. Crain’s extensive experience spans a broad range of conditions, including small intestine and colorectal cancers, breast cancer, prostate cancer, anemia, leukemia, and lymphoma.

Beyond his clinical expertise, Dr. Crain is deeply committed to advancing medical research and improving patient care. His approach to treatment is rooted in compassion and a thorough understanding of complex medical conditions, ensuring each patient receives personalized, comprehensive care.

Recognized for his empathetic nature and unwavering dedication, Dr. Crain strives to achieve the best possible outcomes for his patients and foster a trusting, supportive environment. His lifelong commitment to the fields of oncology and hematology reflects his passion for making a meaningful difference in his patients’ lives.

Michael Kangas serves as the Director of Oncology and Diagnostic Imaging, where he spearheads initiatives that enhance revenue, profitability, productivity, and patient satisfaction within an underserved area. His leadership is instrumental in developing and guiding a highly skilled team of healthcare professionals across multiple clinics, providing comprehensive cancer care and diagnostic imaging services utilizing the most advanced technology. Michael’s commitment is rooted in delivering personalized, high-quality care to each patient, ensuring they receive the support they need throughout their journey.

With extensive expertise in Health Information Management, Electronic Medical Records (EMR), Radiation Therapy, Radiation Oncology, Clinical Operations, Healthcare Compliance, and Regulatory Standards, Michael ensures that all services meet the highest industry standards. He also focuses on monitoring performance, healthcare marketing, and supervisory skills to foster a collaborative, efficient, and patient-centered environment.

In addition to his clinical leadership, Michael actively volunteers with the Merced Cancer Society Foundation as its Executive Director. In this role, he oversees key operational and administrative functions to advance the foundation’s mission of positively impacting residents in the Central Valley. His efforts include community outreach, organizing fundraising events, and leading initiatives to expand the foundation’s support and resources for local cancer patients.

Michael’s dedication to improving healthcare and strengthening community ties highlights his unwavering commitment to healing, hope, and making a meaningful difference in the lives of those he serves.

Anemia is the most prevalent benign blood disorder, impacting more than 3 million Americans, according to the National Heart, Lung, and Blood Institute. Anemia occurs when there is a deficiency of red blood cells or hemoglobin in the blood.

Common Symptoms:

• Weakness
• Shortness of breath
• Dizziness
• Pale skin

Anemia can particularly affect women during pregnancy or their childbearing years due to increased iron demands.

Causes of Anemia:

1. Iron Deficiency Anemia: The most common type, usually caused by blood loss from heavy menstrual cycles or gastrointestinal issues, or from inadequate dietary iron. Treatment typically involves iron supplementation, either orally or intravenously.
2. Aplastic Anemia: A rare condition where the bone marrow fails to produce enough blood cells. Causes may include exposure to toxins, medications, or autoimmune disorders. Diagnosis often requires a bone marrow biopsy. Treatment may include immunosuppressive therapies or bone marrow transplantation.
3. Hemolytic Anemia: Occurs when red blood cells are destroyed faster than they can be produced. Causes range from infections to autoimmune disorders, with treatment addressing underlying causes and sometimes using corticosteroids.

Anemia Treatment depends on its cause, severity, and the individual’s overall health. Here are some common treatment options:

1. Dietary Changes: Increasing intake of iron-rich foods (e.g., red meat, beans, lentils, spinach) and foods high in vitamin B12 and folate (e.g., dairy, eggs, leafy greens).

2. Iron Supplements: Oral or intravenous iron supplements may be prescribed, especially for iron-deficiency anemia.

3. Vitamin Supplements: If the anemia is due to vitamin B12 or folate deficiency, supplements or injections may be recommended.

4. Medications: For anemia related to chronic diseases, medications such as erythropoietin-stimulating agents may be used to stimulate red blood cell production.

5. Blood Transfusions: In severe cases, a transfusion of red blood cells may be necessary to quickly increase hemoglobin levels.

6. Managing Underlying Conditions: Treating the underlying cause of anemia, such as chronic kidney disease, can alleviate symptoms.

7. Bone Marrow Stimulants: In certain cases, treatments that stimulate the bone marrow to produce more red blood cells may be indicated.

It’s essential to consult a healthcare provider for a proper diagnosis and treatment plan tailored to the individual’s specific condition and needs.T

Bleeding disorders are conditions in which the blood does not clot properly, leading to excessive bleeding. At El Portal Comprehensive Cancer Centers, our experts specialize in treating various bleeding disorders, including hemophilia and von Willebrand disease.

• Hemophilia: A genetic disorder mainly affecting males, characterized by excessive bleeding from minor injuries. Modern treatments use synthetic concentrated clotting factors administered intravenously, along with vasopressin to manage bleeding.
• Von Willebrand Disease : An inherited condition caused by a deficiency in a protein essential for blood clotting. Treatment focuses on preventing and managing bleeding episodes, often using synthetic hormones similar to vasopressin.

Treatment options for bleeding disorders like hemophilia and von Willebrand disease (vWD) focus on managing and preventing bleeding episodes. Here are common approaches for each:

Hemophilia:

1. Factor Replacement Therapy:
   • Prophylactic Treatment: Regular infusions of clotting factor concentrates (Factor VIII for Hemophilia A and Factor IX for Hemophilia B) to prevent bleeding episodes.
   • On-Demand Treatment: Administering clotting factors when a bleeding episode occurs.
2. Desmopressin (DDAVP):
   • Used for mild cases of Hemophilia A to stimulate the release of stored Factor VIII from blood vessel lining.
3. Gene Therapy:
   • Investigational treatments aim to provide a functional copy of the missing clotting factor gene, potentially offering a long-term solution.
4. Supportive Treatments:
   • Pain management and rehabilitation for joint health, along with lifestyle adjustments to prevent injury.

von Willebrand Disease (vWD):

1. Desmopressin (DDAVP):
   • The first line of treatment for many with type 1 vWD and some with type 2, as it helps increase von Willebrand factor (vWF) and Factor VIII levels in the blood.
2. Factor Replacement Therapy:
   • Concentrates containing von Willebrand factor and Factor VIII may be used for severe cases or during surgery.
3. Antifibrinolytic Agents:
   • Medications like tranexamic acid may be used to help prevent bleeding during dental procedures or other situations.
4. Avoiding Medications That Affect Clotting:
   • Recommendations to avoid aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) that can increase bleeding risk.
5. Lifestyle and Preventive Measures:
   • Education on avoiding injuries and managing heavy menstrual bleeding in women.

It’s crucial for individuals with bleeding disorders to work closely with a healthcare provider or a specialized hematologist to tailor treatment plans based on their specific needs and to manage their condition effectively.

Treatment options for blood clotting disorders aim to prevent clots from forming, manage existing clots, and reduce the risk of complications. Here are some common approaches based on different types of clotting disorders:

1. Anticoagulant Medications:

– Warfarin (Coumadin): A vitamin K antagonist used to prevent the formation of new clots and to keep existing clots from growing.

– Direct Oral Anticoagulants (DOACs): Medications such as apixaban (Eliquis), rivaroxaban (Xarelto), and dabigatran (Pradaxa) that directly inhibit specific clotting factors.

2. Antiplatelet Medications:

– Aspirin: Often used to prevent clot formation in arteries, particularly in individuals with a history of heart attacks or stroke.

– Clopidogrel (Plavix): Another antiplatelet medication that may be used alone or in combination with aspirin.

3. Thrombolytics:

– Clot Busters: Medications like alteplase (Activase) are used in emergency situations to dissolve large clots quickly, such as those causing strokes or pulmonary embolisms.

4. Compression Therapy:

– Compression Stockings: Used to improve blood flow and reduce swelling in individuals with venous thromboembolism (VTE) or chronic venous insufficiency.

5. Surgery:

– Thrombectomy: Surgical removal of a blood clot may be necessary in severe cases.

– Placement of Inferior Vena Cava (IVC) Filters: A filter may be placed in the IVC to catch clots that may travel from the legs to the lungs, particularly in patients with recurrent clots.

6. Lifestyle and Preventive Measures:

– Dietary Changes: Monitoring vitamin K intake (for patients on warfarin) and maintaining a balanced diet.

– Regular Exercise: Encouraging activity that enhances blood flow, while ensuring safety to avoid injury.

– Hydration: Staying well-hydrated to help maintain proper blood viscosity.

7. Management of Underlying Conditions:

Treating conditions that contribute to clotting disorders, such as atrial fibrillation, hormonal imbalances, or certain types of cancer.

Genetic Counseling:

For hereditary clotting disorders, genetic counseling may be beneficial for affected individuals and their families to understand risks and management strategies.

It’s essential for individuals with blood clotting disorders to work closely with a healthcare provider to develop a tailored treatment plan and to monitor their condition effectively. Regular follow-up and education about the disorder are also crucial parts of effective management.

Myelodysplastic syndromes represent a group of disorders where the bone marrow fails to produce healthy blood cells, leading to insufficient white blood cells, red blood cells, and platelets. Patients with MDS may experience:

• Increased risk of infections due to low white blood cell counts.
• Fatigue and shortness of breath from anemia.
• Excessive bleeding due to low platelet levels.

Treatment options may include blood transfusions, medications to stimulate blood cell production, or immune-suppressive therapies.