Your Strength. Our Knowledge and Experience.

When faced with a cancer diagnosis, the journey ahead is profoundly influenced by the support of the best doctors, options, and support team who work with you.

Mother with her two daughters
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We see you. All of you.

At El Portal Comprehensive Cancer Centers (EPCC), you will benefit from a dedicated team of doctors, nurses, and treatment professionals united by one common goal: an unwavering commitment to your health and well-being. 

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Your fight is personal for us.

We will deliver personalized, world-class care infused with compassion and kindness. Here, you can trust that you will receive cutting-edge treatment along with the highest quality of care.

Compassionate care is premiere at El Portal Cancer Center in the Central Valley of California
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Choose El Portal Comprehensive Cancer Centers as your trusted partner in this journey.

We are a multidisciplinary practice in Central California dedicated to providing care for patients with cancer and diseases of the blood.

Infusion Services

Our Infusion Center prioritizes your health with a commitment to providing excellent care. The first step towards better health is just a drip away, ensuring that you receive the support and treatment you need to enhance your well-being. Learn More information about Infusion Therapy.

Hematology/Oncology

Chemotherapy, Targeted Therapy, Immunotherapy, Iron (Infed, Venofer, Injectafer,  Feraheme, Monoferric), Therapeautic Phlebotomy

Neurology

IVIG, Tysabri, Solu-Medrol, Ocrevus, Leqembi,  Briumvi, Kisunla

IV Infusion/Injectable

Normal Saline (IV Fluids), IV Antibiotics, Prolia, Reclast, Evenity, Dupixent, & Xolair

Rheumatology

Rituxan, Actemra, & Orencia

Gastroenterology

Remicade, Entyvio, Stelera, Cimzia, & Skyryzi

Wellness

Vitamin C infusions, Myers Cocktail infusions,   Glutathione infusions, NAD+ Booster Infusions,  Inflammation and Detoxifying Treatments, Immune  Boosting Drip Treatments, Skin Rejuvenation   Infusions, as well as B12, Lipo-B, and NAD+   Injections

What our patients have to say...

april B. profile pictureapril B.
21:29 22 May 25
I feel fortunate to have been referred to Dr.M as my hematologist. He's been very attentive, thorough, and caring. He is a great Doctor who cares about his patients. Thank you so much Dr. M for caring, as well as to his staff who've been professional and kind also.
Stella Z. profile pictureStella Z.
15:40 19 May 25
Amazing place, front desk and doctors are friendly.
Neveah profile pictureNeveah
18:55 01 May 25
i love it here the ladies here are so nice and have a gentle hand when it comes to the needle. i feel comfortable and unjudged here and enjoy the time i spend here getting to talk to everyone.
Jaimie C. profile pictureJaimie C.
22:43 30 Apr 25
Love every single one of the girls who work in the infusion room. They do such a great job and always make sure we are comfortable and taken care of.
Natasha G. profile pictureNatasha G.
16:32 24 Apr 25
I can’t say enough great things about this place! From the moment I walked in, the staff made me feel more like family than a patient. Everyone is incredibly friendly, professional, and truly goes above and beyond to make sure you're comfortable. They explain every step of the process in detail, which really helps put your mind at ease.

The iron infusion room is spotless—super clean and sanitized, which I really appreciated. Danica and her amazing team are simply the best. Their care, compassion, and warmth made such a difference during my treatment. Once I’m done, I know I’ll truly miss them.

Thank you to the entire staff for making this experience as smooth and comforting as possible. Highly recommend!
Patricia L. profile picturePatricia L.
21:35 21 Apr 25
Thank you Isabel MA for your amazing help, best communication and treatment I received here much lovely service here
Mychelle C. profile pictureMychelle C.
19:00 26 Mar 25
Danika is awesome!!! She always makes sure to make sure I am as comfortable as possible!! The girls are all amazing!!

Share Your Journey with Us!

At El Portal Comprehensive Cancer Centers (EPCC), we believe that every story matters. Your experiences, struggles, and victories can inspire others who are navigating their own cancer journeys. By sharing your story, you not only help build a supportive community but also empower others to find hope and strength.

Working together to explore treatment options and to create a personalized plan based on your diagnosis and lifestyle.

News | Articles | EVENTS

Dr. Alireza Mahmoudieh, M.D.

Dr. Mahmoudieh has been a vital member of El Portal Comprehensive Cancer Centers since 2008, bringing over a decade of dedicated experience to patient care. Before joining our team, he served as the Director of the Prostate Brachytherapy Program at Kaiser Permanente in Sacramento and Roseville, demonstrating his leadership in advanced cancer treatments.

He earned his medical degree from the Albert Szent-Györgyi School of Medicine in Szeged, Hungary, in 1996. With a strong interest in treating head, neck, and breast cancers, Dr. Mahmoudieh specializes in cutting-edge techniques such as Image-Guided Radiation Therapy (IGRT) and Intensity-Modulated Radiation Therapy (IMRT). His expertise extends to treating cancers of the head and neck, lung, gastrointestinal tract, and prostate.

A committed professional, Dr. Mahmoudieh is a member of the American Society for Therapeutic Radiology and Oncology (ASTRO), reflecting his engagement with ongoing developments in cancer treatment and research. His compassionate approach and advanced skill set ensure that each patient receives personalized, state-of-the-art care.

Outside of his professional life, Dr. Mahmoudieh enjoys traveling with his son and daughter, as well as reading and playing racquetball, embracing a balanced and active lifestyle. His dedication to both his patients and his personal passions makes him a trusted partner in your journey toward health.

Dr. Osman Elhanafy, Ph.D

Dr. Elhanafy is a highly respected Associate Professor of Medical Physics and serves as the Chief Medical Physicist at El Portal Comprehensive Cancer Centers since July 2013. He earned his Ph.D. in Medical Physics from the University of Wisconsin, Madison—where he began his foundational training and completed his thesis—in 2013, building on his initial joining of the university in 1999.

 With specialized training in advanced radiation oncology techniques—such as Intensity-Modulated Radiation Therapy (IMRT), High-Dose Rate Brachytherapy (HDR), Stereotactic Radiosurgery (SRS), Total Body Irradiation (TBI), Quality Assurance, and Radiobiology—Dr. Elhanafy brings a wealth of expertise to patient care. His dedication to the field is evident through numerous published research articles, as well as awards recognizing his leadership in organizing conferences, training sessions, lectures, and workshops.

Beyond his impressive credentials, Dr. Elhanafy is deeply committed to advancing medical physics and ensuring the best possible outcomes for his patients. His compassionate approach, combined with his extensive knowledge, makes him a trusted partner in your cancer care journey.

Outside of his professional pursuits, he values spending quality time with his family, reflecting his genuine care and balance in life.

Dr. Harish Ahuja, M.D.

Dr. Ahuja is a distinguished, board-certified Medical Oncologist with extensive training in medical hematology. He has refined his expertise at renowned institutions such as Tata Memorial Hospital, UCLA School of Medicine, and Roswell Park, under the mentorship of esteemed hematologists including Dr. S.H. Advani, Dr. Michael Caligiuri, and Dr. M.J. Cline.

With over 25 years of experience in both hematology and oncology, Dr. Ahuja offers a deep well of knowledge and a compassionate approach to patient care at El Portal Cancer Center. His dedication to advancing the field is reflected through active membership in prestigious professional organizations, including the American Society of Hematology, the American Society of Clinical Oncology, the European Society of Medical Oncology, and the Indian Society of Medical and Pediatric Oncology.

A passionate researcher, Dr. Ahuja has contributed significantly to ongoing scientific advancements—serving on the NRG Breast Committee and the Rare Subtype Committee, and acting as Principal Investigator for the “CROWN” NCORP study. His commitment to clinical excellence and groundbreaking research underscores his dedication to improving outcomes for his patients.

Outside of his professional pursuits, Dr. Ahuja values spending quality time with his family, and enjoys hiking and traveling, embracing life outside the clinic with the same dedication he brings to his medical practice. His compassionate nature and extensive experience make him a trusted partner in your cancer care journey.

Dr. Sidney Crain, M.D.

Dr. Crain is a highly experienced and board-certified Medical Oncologist and Hematologist with over 45 years of dedicated service in the medical field. Throughout his distinguished career, he has established himself as a leading expert in the diagnosis, treatment, and prevention of various cancers and blood disorders.

He earned his medical degree from the University of Illinois College of Medicine in 1977 and is actively affiliated with esteemed institutions, including Adventist Health St. Helena. Dr. Crain’s extensive experience spans a broad range of conditions, including small intestine and colorectal cancers, breast cancer, prostate cancer, anemia, leukemia, and lymphoma.

Beyond his clinical expertise, Dr. Crain is deeply committed to advancing medical research and improving patient care. His approach to treatment is rooted in compassion and a thorough understanding of complex medical conditions, ensuring each patient receives personalized, comprehensive care.

Recognized for his empathetic nature and unwavering dedication, Dr. Crain strives to achieve the best possible outcomes for his patients and foster a trusting, supportive environment. His lifelong commitment to the fields of oncology and hematology reflects his passion for making a meaningful difference in his patients’ lives.

Michael Kangas

Michael Kangas serves as the Director of Oncology and Diagnostic Imaging, where he spearheads initiatives that enhance revenue, profitability, productivity, and patient satisfaction within an underserved area. His leadership is instrumental in developing and guiding a highly skilled team of healthcare professionals across multiple clinics, providing comprehensive cancer care and diagnostic imaging services utilizing the most advanced technology. Michael’s commitment is rooted in delivering personalized, high-quality care to each patient, ensuring they receive the support they need throughout their journey.

With extensive expertise in Health Information Management, Electronic Medical Records (EMR), Radiation Therapy, Radiation Oncology, Clinical Operations, Healthcare Compliance, and Regulatory Standards, Michael ensures that all services meet the highest industry standards. He also focuses on monitoring performance, healthcare marketing, and supervisory skills to foster a collaborative, efficient, and patient-centered environment.

In addition to his clinical leadership, Michael actively volunteers with the Merced Cancer Society Foundation as its Executive Director. In this role, he oversees key operational and administrative functions to advance the foundation’s mission of positively impacting residents in the Central Valley. His efforts include community outreach, organizing fundraising events, and leading initiatives to expand the foundation’s support and resources for local cancer patients.

Michael’s dedication to improving healthcare and strengthening community ties highlights his unwavering commitment to healing, hope, and making a meaningful difference in the lives of those he serves.

Paul Mosher

Paul I. Mosher is a highly accomplished business professional with extensive experience in healthcare management, medical device sales, and community service. Currently, he proudly serves as the Physician Liaison and Business Development Coordinator at El Portal Comprehensive Cancer Center. In this role, Paul collaborates closely with our dedicated medical team to facilitate patient-centered care, foster strong relationships with our physicians, and support the center’s mission of providing the highest quality cancer treatment.

With expertise in business development, leadership, relationship management, and healthcare technology, Paul is a dedicated and effective communicator committed to exceptional service and compassionate support. His collaborative approach helps ensure that patients receive not only cutting-edge treatment but also personalized care rooted in trust and understanding. Additionally, Paul brings ten years of non-profit experience to our board of directors, furthering his devotion to community health and service.

Paul holds a Bachelor of Business in Business Marketing from Boise State University. He is actively involved in his community, volunteering with various Merced non-profits and churches. Outside of work, Paul enjoys spending quality time with his family and playing golf whenever he can.

Infusion Therapy - Conditions Treated

Infusions are used to treat a wide range of medical conditions, including:

  • Cancer: Chemotherapy agents, targeted therapies, and immunotherapies are often administered via infusion to treat various cancers such as breast, lung, and leukemia.
  • Autoimmune Disorders: Conditions like rheumatoid arthritis, lupus, and multiple sclerosis may be treated with biological agents delivered through infusions to help regulate the immune system.
  • Infections: Severe infections might require antibiotics delivered through infusion for immediate and effective treatment.
  • Nutritional Support: Patients unable to eat or absorb nutrients through the gastrointestinal tract may receive nutritional solutions (Total Parenteral Nutrition, TPN) via infusion.
  • Pain Management: For chronic pain conditions, infusions of medications such as opioids or analgesics may provide relief.
  • Hydration and Electrolyte Replacement: IV fluids are commonly used for rehydration in patients with severe dehydration or electrolyte imbalances.

Risk Factors for Infusion Therapy

While infusion therapy is generally safe, certain factors may increase the risk of complications, including:

  • Allergies:Some patients may have allergic reactions to medications being infused.
  • Infection Risk:The insertion of IV lines can lead to infections if not performed under sterile conditions.
  • Pre-existing Conditions:Patients with compromised immune systems, heart conditions, or kidney issues may face additional risks.
  • Substance Interactions:Patients should disclose all medications, supplements, and herbal products they are taking, as interactions can occur.


Timing of Treatments:
The timing of infusion treatments varies based on the condition being treated:

  • Cancer Patients: Infusion schedules can be based on specific chemotherapy regimens, often occurring every few weeks or as prescribed by an oncologist.
  • Autoimmune Disorders: Infusions may be scheduled monthly or as part of a broader treatment plan based on symptoms and disease activity.
  • Acute Conditions: Infusions for infections or severe hydration may occur as needed, often in a hospital setting.

Side Effects of Infusion Therapy

Side effects of infusion therapy can vary depending on the type of medication and individual patient factors. Common side effects include:

  • Infusion Reactions:Fever, chills, or rashes occurring during or shortly after the infusion.
  • Nausea and Vomiting:Particularly common with chemotherapy agents.
  • Fatigue:Many patients experience tiredness following infusion sessions.
  • Infections:Risks associated with the use of IV lines.
  • Local Reactions: Bruising, swelling, or inflammation at the injection site.

Success Rates of Infusion Therapy

The success rate of infusion therapy depends on several factors, including:

  • Type of Condition: Certain cancer treatments administered via infusion can have high cure rates, especially when applied at early stages.
  • Individual Response: How a patient responds to the specific medication influences effectiveness.
  • Comprehensive Treatment Plan: Optimizing infusion therapy as part of a broader treatment strategy (including surgery, radiotherapy, etc.) can enhance success rates.


For example:

  • Chemotherapy: May lead to significant tumor shrinkage or remission in many cancer patients.
  • Biologics for Autoimmunity: Often result in substantial improvements in symptoms and quality of life for patients with autoimmune diseases.

Support for Your Physical Well-Being

Caring for someone with cancer can make maintaining your own health seem difficult. To effectively care for your loved one, it’s vital to schedule time for your own medical appointments and self-care routines. Prioritizing your health ensures you have the strength and energy to continue providing support. Incorporate self-care practices such as maintaining a balanced diet, getting adequate sleep, engaging in regular physical activity, and practicing relaxation techniques like deep breathing or meditation.

There are resources to help you stay physically active and connected to the world around you. If you need help finding services in your area, contact an EPCC social worker.

Emotional Support

The emotional toll of caregiving can lead to feelings of isolation and exhaustion. The following resources can help nurture your emotional well-being and provide strategies for maintaining balance while caring for your loved one.

Our social workers are available to offer counseling and connect you with local support services. To speak with a licensed social worker, contact your nearest EPCC location during business hours.

Important: In case of an emergency, do not leave a message—call 911 directly.

Social Support and Practical Help

Connecting with others and carving out time for yourself can be difficult. Getting assistance with everyday tasks can free up energy and reduce stress.

  • Reducing Stress and Anxiety: Share your feelings with family and friends so they understand your needs. Consider designating one or two people as primary contacts to communicate important updates or coordinate help.
  • Organizing Support: Organizing support for cancer patients can make a significant difference in their quality of life and treatment experience. Here are some ideas:
  • Create a Care Calendar or Schedule: Use tools like Lotsa Helping Hands or a shared online calendar to coordinate tasks such as meal preparation, transportation, errands, and childcare.
  • Designate Support Roles: Assign specific responsibilities to friends or family members—e.g., one person manages appointments, another handles meals, and someone else provides emotional support.
  • Use Digital Platforms: Set up a private CaringBridge site or Facebook group for updates, sharing needs, and organizing volunteer efforts.
  • Meal Train: Organize a meal delivery schedule through services like MealTrain.com to ensure consistent nutritious meals.
  • Transportation Assistance: Coordinate rides to treatment appointments through community programs, local volunteer driver services, or rideshare apps.
  • Host Support Groups: Establish or join local or virtual support groups for patients and caregivers to share experiences and advice.
  • Organize Practical Help: Arrange for cleaning services, home repairs, or pet care through local providers or community resources.
  • Spiritual and Emotional Support: Connect with local chaplain services, spiritual care providers, or mental health counselors who can offer guidance and comfort.
  • Fundraising and Resources: Set up crowdfunding campaigns or organize community fundraising events to support medical expenses or related needs.
  • Encourage Self-Care and Reflection: Support the patient in incorporating activities like meditation, journaling, or nature walks into their routine, and facilitate access to these resources.


Implementing even a few of these strategies can greatly ease the burden on patients and caregivers, fostering a supportive community around their treatment and recovery.

Resources in Your Area:

  • Meal Delivery: Meals on Wheels — check their website for local providers.
  • Transportation: Local transportation services in the Central Valley, or the American Cancer Society Road to Recovery (800-227-2345).
  • Cleaning Services:
    Modesto:
    MaidPro Modesto — Professional cleaning services including residential and light commercial cleaning.
    Sweet Home Cleaning — Offers regular and deep cleaning options for homes.

    Merced:
    Maid in Merced — House cleaning services with flexible scheduling.
    Merced Cleaning Service — Residential cleaning, move-in/move-out cleaning, and special deep cleaning.

    Manteca:
    Manteca Cleaning Service — Residential and commercial cleaning, including carpet and upholstery cleaning.
    Simply Clean Manteca — Home cleaning services tailored to your needs.


Please note that it’s advisable to verify current availability, reviews, and insurance coverage before hiring any service.

  • Home Care Support: Consult your medical team for referrals suitable to your needs, with local providers available in Modesto, Merced, and Manteca.

Caring for Your Spirit

Spirituality can mean different things to each person, often related to finding purpose and connection in life. As a caregiver, taking time for reflection and nurturing your spirit is essential but can be overlooked.

Resources and practices such as meditation, guided visualization, journaling, spending time in nature, or connecting with a spiritual care provider can be helpful.

Connecting with Spiritual Support:
Start by contacting your local hospital’s pastoral care or chaplain services. They can connect you with a non-denominational chaplain or spiritual counselor who can offer support and guidance aligned with your beliefs or preferences.

If you need additional assistance or specific resources tailored to your area, please contact a social worker at your EPCC location.