Your Strength. Our Knowledge and Experience.

The most critical warning sign of skin cancer is the appearance of a new spot on the skin or changes in an existing spot that seem abnormal. Following the A B C D E guidelines can help you identify the common signs of skin cancer:

• Asymmetry:One half of a mole (or birthmark) does not match the other half.
• Border:Edges are irregular, ragged, notched, or blurred.
• Color:The color is uneven, often featuring different shades of brown or black, along with patches of pink, red, white, or blue.
• Diameter:The spot is larger than 6 millimeters across (about the size of a pencil eraser).
• Evolving:The mole is changing in size, shape, color, or elevation. 

Skin cancer is typically identified first by a healthcare professional during an examination of an unusual area on the skin. However, determining whether it is cancerous requires removal and subsequent testing, known as a biopsy. This is the only reliable method to confirm a skin cancer diagnosis.

You may have your biopsy performed in a dermatologist’s office or as an outpatient procedure in a hospital or clinic, depending on the size and location of the abnormal area. Local anesthesia is usually administered to ensure your comfort.

There are four common types of skin biopsies:

• Punch Biopsy:A sharp, hollow tool is used to remove a circle of tissue from the abnormal area.
• Incisional Biopsy:A scalpel is employed to remove a portion of the growth.
• Excisional Biopsy:The entire growth and some surrounding tissue are removed with a scalpel.
• Shave Biopsy:A thin, sharp blade is used to shave off the abnormal growth.

If there is a possibility of melanoma, dermatologists will generally avoid simply shaving or cauterizing the growth. Instead, an excisional biopsy will be performed, or if the growth is too large, a tissue sample will be collected.

Upon receiving a biopsy confirmation of skin cancer, you will be referred to a specialized oncologist for further evaluation and care. Understanding the extent, or stage, of your cancer is crucial, whether you have melanoma or nonmelanoma skin cancer. Staging involves a meticulous assessment to determine how thick the tumor is and whether it has metastasized to other parts of the body. If the tumor is particularly thick, your doctor may recommend chest x-rays, blood tests, and imaging scans of the liver, bones, and brain.

Knowing the stage of your cancer enables your oncologist to:

• Assess the seriousness of your cancer and your chances for survival
• Formulate the most effective treatment plan for your unique situation
• Identify clinical trials that may present additional treatment options

In some cases, your oncologist may need to examine your lymph nodes to accurately stage the cancer. Surgical procedures may be part of the treatment plan to remove cancerous lymph nodes, which can aid in managing the disease.

Staging Criteria
Staging is based on several key factors:

• The size of the tumor
• How deeply it has penetrated below the surface of the skin
• Whether it has spread to nearby lymph nodes or other organs

Oncologists utilize Roman numerals I through IV to designate the cancer stage. Stage I indicates small tumors that are confined to their original site, while Stage IV signifies advanced cancer that has spread to distant sites in the body.

Nonmelanoma Skin Cancer Staging
The stages of nonmelanoma skin cancer are as follows:

• Stage 0: The cancer is localized to the top layer of skin, classified as carcinoma in situ.
• Stage I: The tumor measures 2 centimeters (approximately three-quarters of an inch) or smaller.
• Stage II: The tumor exceeds 2 centimeters in diameter.
• Stage III: The cancer has spread beyond the skin to underlying tissues such as cartilage, muscle, or bone, or to nearby lymph nodes, but not to distant locations.
• Stage IV: The cancer has metastasized to other areas in the body.

Melanoma Staging
The staging for melanoma specifically is defined as follows:

• Stage 0: Melanoma cells are confined to the outer layer of skin (epidermis) and have not invaded deeper tissues.
• Stage I: In Stage I, the melanoma is considered thin:
  • The tumor is no thicker than 1 millimeter (1/25 inch) and may show signs of ulceration (a scraped appearance).
  • Alternatively, the tumor measures between 1 and 2 millimeters thick without ulceration, and melanoma cells have not spread to nearby lymph nodes.
• Stage II: At this stage, the tumor is at least 1 millimeter thick:
  • It may be between 1 and 2 millimeters thick and present with ulceration.
  • Alternatively, the tumor may be greater than 2 millimeters thick, potentially with ulceration, but has not yet spread to nearby lymph nodes.
• Stage III: This indicates that melanoma has spread to nearby lymph nodes or to tissues just outside the original tumor without affecting the lymph nodes.
• Stage IV: At this advanced stage, melanoma cells have metastasized to other organs, lymph nodes, or distant skin areas.
• Recurrent: Recurrent disease indicates that cancer has returned after treatment, either in the original site or in a new location within the body.

There are various approaches to treating skin cancer, and your oncologist will work closely with you to determine the most effective combination of therapies based on the stage of cancer and your overall health. We at El Portal Comprehensive Cancer Centers are dedicated to providing you with comprehensive care tailored to your needs, ensuring you receive the support, guidance, and treatment necessary for your journey toward recovery.

Nonmelanoma Skin Cancer Treatments

In some cases, the entire nonmelanoma skin cancer may be removed during the biopsy, which means no further treatment is necessary. However, if additional treatment is required, your doctor will outline the available options.

There are six primary types of nonmelanoma skin cancer treatments, which may be used individually or in combination:

1. Surgery
2. Chemotherapy
3. Photodynamic therapy
4. Radiation therapy
5. Biologic therapy
6. Targeted therapy

Melanoma Skin Cancer Treatments

Melanoma treatment encompasses nearly all the same options as nonmelanoma skin cancer, with the exception of photodynamic therapy.

Skin Cancer Treatment Options

Your oncologist can provide detailed explanations of the following surgical techniques:

• Wide-Local Excision (WLE): This common approach involves numbing the area and surgically removing the cancer along with a margin of surrounding healthy skin. The margin is examined microscopically to ensure all cancer cells have been excised, and the required margin size will depend on the tumor’s dimensions. In some cases, nearby lymph nodes may also be removed.
• Mohs Surgery: This technique is particularly beneficial for skin cancer treatment. The surgeon numbs the area and removes thin layers of the tumor, examining each layer under a microscope for cancer cells. The process continues until no cancerous cells are detected, ensuring complete tumor removal while preserving as much healthy tissue as possible.
• Electrodesiccation and Curettage: This method is ideal for small basal cell skin cancers. The doctor numbs the area, removes the cancer using a curette (a spoon-shaped surgical instrument), and then employs an electric current to control bleeding and eliminate any remaining cancer cells. This procedure tends to be quick and straightforward.
• Cryosurgery: This option is suitable for patients who may not tolerate other surgical methods. Cryosurgery employs extreme cold, typically generated from liquid nitrogen, to treat early-stage or very thin skin cancer lesions. While effective, this approach may cause swelling and could damage nerves in the area, leading to temporary loss of sensation.
• Laser Surgery: This technique involves using a focused beam of light to target and destroy cancer cells. It is primarily utilized for superficial growths confined to the outer layer of skin.
• Skin Grafting: Occasionally, grafts are necessary to cover openings left by surgical removal. In this procedure, the surgeon numbs the area and removes a patch of healthy skin from another part of your body, such as the thigh, to cover the excised area. It is important to provide special care to the graft site during the healing process.
• Lymphadenectomy: This surgical procedure may be employed in the case of melanoma, wherein lymph nodes are removed for evaluation. The removed tissue is examined under a microscope for cancer cells.
• Sentinel Lymph Node Biopsy: During this procedure, the sentinel lymph node—the first node likely to receive cancer spread from the tumor—is surgically removed. A radioactive substance and/or blue dye is injected near the tumor site to track the flow to the lymph nodes. If no cancer cells are found in the sentinel node, additional nodes may not need to be excised, making this a useful technique within melanoma treatment plans.

Receiving a prostate cancer diagnosis can be overwhelming, and there are important decisions to be made. It’s natural to have questions, and we are here to help you navigate your options and understand what lies ahead. You’ll learn about your cancer care team and what to expect as you embark on this journey.

What Type of Doctor Should You See First After a Prostate Cancer Diagnosis?

Typically, a urologist will perform the biopsy that confirms the presence of prostate cancer and assesses its aggressiveness. Following this initial diagnosis, we recommend scheduling a consultation with an oncologist. Our dedicated oncologists are well-versed in the latest treatment options, ensuring you receive therapies tailored specifically for you.

Your oncologist will help you understand the growth pattern of the cancer and how it may evolve moving forward. The biopsy results, combined with other diagnostic tests, will provide the necessary information to determine both the stage and grade of your prostate cancer.

Staging Prostate Cancer

Using the results from your biopsy and additional diagnostic tests, your oncologist will ascertain the stage of your prostate cancer. Further imaging or scans may be required to identify whether cancer cells have extended beyond the prostate.

Gleason Score and Grading

The Gleason score, included in your biopsy report, indicates how much the cancer cells have altered in various parts of the prostate. This grading aids in determining whether immediate treatment is necessary.

The Gleason score is a system used to grade prostate cancer based on how aggressive and likely it is to spread. It is determined by examining cancer cells under a microscope and assigning them a score from 1 to 5.

Grading:
1-2: Well-differentiated, least aggressive
3-4: Moderately differentiated
5: Poorly differentiated, most aggressive

Gleason scores are subject to interpretation and may vary slightly between pathologists. It is important to discuss your Gleason score with your healthcare provider to understand its implications and treatment options.

Preparing for Your First Oncology Appointment

Your first oncology appointment is essential for gathering important information, but it can be overwhelming. We suggest bringing a notebook or using your smartphone to take notes during the appointment. This will help you keep track of important details and any questions that arise.

We strongly encourage you to bring a friend or loved one for support. They can take notes, ask questions that might be on your mind, and provide reassurance.

Additionally, please bring your health records, including any prostate cancer test results, recent imaging scans, your insurance card, and a list of medications or supplements you’re currently taking.

Questions to Discuss with Your Oncologist

• How soon do I need to decide on a treatment plan?
• If “watchful waiting” is recommended, how often should I return for follow-up testing?
• What treatment options do you suggest when the time comes to proceed?
• What should I expect during future appointments?
• Are there lifestyle changes (in diet, exercise, rest, or stress management) I should consider?
• How should I manage any symptoms affecting my daily life?
• Are there any activities I should avoid or incorporate into my routine?
• Can I take nutritional supplements or vitamins to support my prostate health?
• Should my family and I consider genetic testing to check for hereditary risk?
• What supportive care resources are available through your practice or community organizations?

Feeling confident about your prostate cancer diagnosis and treatment plan is vital, even if it begins with watchful waiting. Many patients choose to seek a second opinion, and our oncologists are completely supportive of this decision. Insurance coverage for second opinions is often available, so we recommend contacting your insurance provider to verify your benefits before scheduling an appointment.

You Are Not Alone on Your Prostate Cancer Journey

At El Portal Comprehensive Cancer Centers, we are committed to supporting you throughout your entire journey. With convenient locations across Central California, we are here to offer you compassionate care and guidance every step of the way. Together, we will navigate this path to achieve the best possible outcome for your health and well-being.

Dr. Mahmoudieh has been a vital member of El Portal Comprehensive Cancer Centers since 2008, bringing over a decade of dedicated experience to patient care. Before joining our team, he served as the Director of the Prostate Brachytherapy Program at Kaiser Permanente in Sacramento and Roseville, demonstrating his leadership in advanced cancer treatments.

He earned his medical degree from the Albert Szent-Györgyi School of Medicine in Szeged, Hungary, in 1996. With a strong interest in treating head, neck, and breast cancers, Dr. Mahmoudieh specializes in cutting-edge techniques such as Image-Guided Radiation Therapy (IGRT) and Intensity-Modulated Radiation Therapy (IMRT). His expertise extends to treating cancers of the head and neck, lung, gastrointestinal tract, and prostate.

A committed professional, Dr. Mahmoudieh is a member of the American Society for Therapeutic Radiology and Oncology (ASTRO), reflecting his engagement with ongoing developments in cancer treatment and research. His compassionate approach and advanced skill set ensure that each patient receives personalized, state-of-the-art care.

Outside of his professional life, Dr. Mahmoudieh enjoys traveling with his son and daughter, as well as reading and playing racquetball, embracing a balanced and active lifestyle. His dedication to both his patients and his personal passions makes him a trusted partner in your journey toward health.

Dr. Elhanafy is a highly respected Associate Professor of Medical Physics and serves as the Chief Medical Physicist at El Portal Comprehensive Cancer Centers since July 2013. He earned his Ph.D. in Medical Physics from the University of Wisconsin, Madison—where he began his foundational training and completed his thesis—in 2013, building on his initial joining of the university in 1999.

 With specialized training in advanced radiation oncology techniques—such as Intensity-Modulated Radiation Therapy (IMRT), High-Dose Rate Brachytherapy (HDR), Stereotactic Radiosurgery (SRS), Total Body Irradiation (TBI), Quality Assurance, and Radiobiology—Dr. Elhanafy brings a wealth of expertise to patient care. His dedication to the field is evident through numerous published research articles, as well as awards recognizing his leadership in organizing conferences, training sessions, lectures, and workshops.

Beyond his impressive credentials, Dr. Elhanafy is deeply committed to advancing medical physics and ensuring the best possible outcomes for his patients. His compassionate approach, combined with his extensive knowledge, makes him a trusted partner in your cancer care journey.

Outside of his professional pursuits, he values spending quality time with his family, reflecting his genuine care and balance in life.

Dr. Ahuja is a distinguished, board-certified Medical Oncologist with extensive training in medical hematology. He has refined his expertise at renowned institutions such as Tata Memorial Hospital, UCLA School of Medicine, and Roswell Park, under the mentorship of esteemed hematologists including Dr. S.H. Advani, Dr. Michael Caligiuri, and Dr. M.J. Cline.

With over 25 years of experience in both hematology and oncology, Dr. Ahuja offers a deep well of knowledge and a compassionate approach to patient care at El Portal Cancer Center. His dedication to advancing the field is reflected through active membership in prestigious professional organizations, including the American Society of Hematology, the American Society of Clinical Oncology, the European Society of Medical Oncology, and the Indian Society of Medical and Pediatric Oncology.

A passionate researcher, Dr. Ahuja has contributed significantly to ongoing scientific advancements—serving on the NRG Breast Committee and the Rare Subtype Committee, and acting as Principal Investigator for the “CROWN” NCORP study. His commitment to clinical excellence and groundbreaking research underscores his dedication to improving outcomes for his patients.

Outside of his professional pursuits, Dr. Ahuja values spending quality time with his family, and enjoys hiking and traveling, embracing life outside the clinic with the same dedication he brings to his medical practice. His compassionate nature and extensive experience make him a trusted partner in your cancer care journey.

Dr. Crain is a highly experienced and board-certified Medical Oncologist and Hematologist with over 45 years of dedicated service in the medical field. Throughout his distinguished career, he has established himself as a leading expert in the diagnosis, treatment, and prevention of various cancers and blood disorders.

He earned his medical degree from the University of Illinois College of Medicine in 1977 and is actively affiliated with esteemed institutions, including Adventist Health St. Helena. Dr. Crain’s extensive experience spans a broad range of conditions, including small intestine and colorectal cancers, breast cancer, prostate cancer, anemia, leukemia, and lymphoma.

Beyond his clinical expertise, Dr. Crain is deeply committed to advancing medical research and improving patient care. His approach to treatment is rooted in compassion and a thorough understanding of complex medical conditions, ensuring each patient receives personalized, comprehensive care.

Recognized for his empathetic nature and unwavering dedication, Dr. Crain strives to achieve the best possible outcomes for his patients and foster a trusting, supportive environment. His lifelong commitment to the fields of oncology and hematology reflects his passion for making a meaningful difference in his patients’ lives.

Michael Kangas serves as the Director of Oncology and Diagnostic Imaging, where he spearheads initiatives that enhance revenue, profitability, productivity, and patient satisfaction within an underserved area. His leadership is instrumental in developing and guiding a highly skilled team of healthcare professionals across multiple clinics, providing comprehensive cancer care and diagnostic imaging services utilizing the most advanced technology. Michael’s commitment is rooted in delivering personalized, high-quality care to each patient, ensuring they receive the support they need throughout their journey.

With extensive expertise in Health Information Management, Electronic Medical Records (EMR), Radiation Therapy, Radiation Oncology, Clinical Operations, Healthcare Compliance, and Regulatory Standards, Michael ensures that all services meet the highest industry standards. He also focuses on monitoring performance, healthcare marketing, and supervisory skills to foster a collaborative, efficient, and patient-centered environment.

In addition to his clinical leadership, Michael actively volunteers with the Merced Cancer Society Foundation as its Executive Director. In this role, he oversees key operational and administrative functions to advance the foundation’s mission of positively impacting residents in the Central Valley. His efforts include community outreach, organizing fundraising events, and leading initiatives to expand the foundation’s support and resources for local cancer patients.

Michael’s dedication to improving healthcare and strengthening community ties highlights his unwavering commitment to healing, hope, and making a meaningful difference in the lives of those he serves.

Caring for someone with cancer can make maintaining your own health seem difficult. To effectively care for your loved one, it’s vital to schedule time for your own medical appointments and self-care routines. Prioritizing your health ensures you have the strength and energy to continue providing support. Incorporate self-care practices such as maintaining a balanced diet, getting adequate sleep, engaging in regular physical activity, and practicing relaxation techniques like deep breathing or meditation.

There are resources to help you stay physically active and connected to the world around you. If you need help finding services in your area, contact an EPCC social worker.

The emotional toll of caregiving can lead to feelings of isolation and exhaustion. The following resources can help nurture your emotional well-being and provide strategies for maintaining balance while caring for your loved one.

Our social workers are available to offer counseling and connect you with local support services. To speak with a licensed social worker, contact your nearest EPCC location during business hours.

Important: In case of an emergency, do not leave a message—call 911 directly.

Connecting with others and carving out time for yourself can be difficult. Getting assistance with everyday tasks can free up energy and reduce stress.

• Reducing Stress and Anxiety: Share your feelings with family and friends so they understand your needs. Consider designating one or two people as primary contacts to communicate important updates or coordinate help.
• Organizing Support: Organizing support for cancer patients can make a significant difference in their quality of life and treatment experience. Here are some ideas:

• Create a Care Calendar or Schedule: Use tools like Lotsa Helping Hands or a shared online calendar to coordinate tasks such as meal preparation, transportation, errands, and childcare.
• Designate Support Roles: Assign specific responsibilities to friends or family members—e.g., one person manages appointments, another handles meals, and someone else provides emotional support.
• Use Digital Platforms: Set up a private CaringBridge site or Facebook group for updates, sharing needs, and organizing volunteer efforts.
• Meal Train: Organize a meal delivery schedule through services like MealTrain.com to ensure consistent nutritious meals.
• Transportation Assistance: Coordinate rides to treatment appointments through community programs, local volunteer driver services, or rideshare apps.
• Host Support Groups: Establish or join local or virtual support groups for patients and caregivers to share experiences and advice.
• Organize Practical Help: Arrange for cleaning services, home repairs, or pet care through local providers or community resources.
• Spiritual and Emotional Support: Connect with local chaplain services, spiritual care providers, or mental health counselors who can offer guidance and comfort.
• Fundraising and Resources: Set up crowdfunding campaigns or organize community fundraising events to support medical expenses or related needs.
• Encourage Self-Care and Reflection: Support the patient in incorporating activities like meditation, journaling, or nature walks into their routine, and facilitate access to these resources.

Implementing even a few of these strategies can greatly ease the burden on patients and caregivers, fostering a supportive community around their treatment and recovery.

Resources in Your Area:

• Meal Delivery: Meals on Wheels — check their website for local providers.
• Transportation: Local transportation services in the Central Valley, or the American Cancer Society Road to Recovery (800-227-2345).
• Cleaning Services:
  Modesto:
  MaidPro Modesto — Professional cleaning services including residential and light commercial cleaning.
  Sweet Home Cleaning — Offers regular and deep cleaning options for homes.
  
  Merced:
  Maid in Merced — House cleaning services with flexible scheduling.
  Merced Cleaning Service — Residential cleaning, move-in/move-out cleaning, and special deep cleaning.
  
  Manteca:
  Manteca Cleaning Service — Residential and commercial cleaning, including carpet and upholstery cleaning.
  Simply Clean Manteca — Home cleaning services tailored to your needs.

Please note that it’s advisable to verify current availability, reviews, and insurance coverage before hiring any service.

• Home Care Support: Consult your medical team for referrals suitable to your needs, with local providers available in Modesto, Merced, and Manteca.

Spirituality can mean different things to each person, often related to finding purpose and connection in life. As a caregiver, taking time for reflection and nurturing your spirit is essential but can be overlooked.

Resources and practices such as meditation, guided visualization, journaling, spending time in nature, or connecting with a spiritual care provider can be helpful.

Connecting with Spiritual Support:
Start by contacting your local hospital’s pastoral care or chaplain services. They can connect you with a non-denominational chaplain or spiritual counselor who can offer support and guidance aligned with your beliefs or preferences.

If you need additional assistance or specific resources tailored to your area, please contact a social worker at your EPCC location.

A cancer diagnosis can profoundly impact family dynamics, routines, and relationships. Family members may experience their own emotional stresses, worry about the patient’s health, and take on new caregiving roles. Communication can become more open or strained, and adjusting to changes in roles—such as caregiver, supporter, or decision-maker—requires flexibility and understanding. Supporting the emotional needs of each family member and seeking family counseling or support groups can help the entire family navigate this challenging time together.

Returning to work after cancer treatment often requires adjustments to accommodate ongoing health needs, fatigue, or emotional changes. Many survivors find they need to modify their schedules, work part-time, or explore flexible work arrangements. Open communication with employers about your needs can foster understanding and support. Establishing a new routine that balances recovery with professional responsibilities helps rebuild confidence and maintain a sense of purpose.

Psychological resilience plays a crucial role in survivorship. Many survivors face emotional challenges such as anxiety, depression, or fear of recurrence. Prioritizing mental health through counseling, support groups, mindfulness practices, or relaxation techniques can foster emotional well-being. Recognizing that emotional healing is part of the journey encourages survivors to seek help when needed and to nurture a positive outlook.

Most colorectal cancers are detected during routine screenings, which have become more streamlined, making it easier for you to stay on track with your health. It’s essential to know the types of tests available for early detection of colorectal cancer.

1. Colonoscopy: This procedure involves using a long, flexible tube with a camera to examine the entire colon and rectum. It’s the most comprehensive screening method and allows for the removal of polyps during the exam.
2. Flexible Sigmoidoscopy: Similar to a colonoscopy but examines only the rectum and the lower part of the colon. It requires less preparation and can be done in a doctor’s office.
3. Fecal Occult Blood Test (FOBT): This non-invasive test checks for hidden blood in the stool, which can be a sign of cancer or polyps. It usually requires multiple stool samples over several days.
4. Fecal Immunochemical Test (FIT): Another stool test that detects blood in the stool using antibodies. It’s more specific than the FOBT and does not require dietary restrictions.
5. CT Colonography (Virtual Colonoscopy): This imaging test uses X-rays and computer technology to create detailed pictures of the colon. It’s less invasive than a traditional colonoscopy but cannot remove polyps.
6. DNA Stool Test: This test analyzes stool samples for specific DNA markers that may indicate the presence of cancer or pre-cancerous conditions. It can be more comprehensive in its approach.
7. Blood Tests: While not used for routine screening, certain blood tests may help assess liver function or detect tumor markers in some cases.

These tests help identify colorectal cancer or pre-cancerous polyps early when treatment is most effective. It’s important to discuss with a healthcare provider which screening method is best suited for individual risk factors and medical history.

Plainly put: Regular screening can save lives!

During the early stages of colorectal cancer, there are typically no visible signs of its presence, making screenings crucial for identifying pre-cancerous and cancerous areas while they are still small. Early detection often leads to fewer treatment demands and greatly increases success rates.

Although it might feel uncomfortable, please don’t shy away from scheduling your screening, especially if you are over 40. Taking this step with your primary care physician can help you create a personalized colon cancer screening plan that is right for you.

Several screening tests are available, ranging from convenient at-home options to more comprehensive procedures performed at healthcare facilities. Your doctor will work with you to select the best method based on your age and family history.

At-Home Screening Options

These tests allow you to screen in the comfort of your home without extensive preparation, though they may carry risks of false positives.

1. At-Home Testing for Colorectal Cancer: If you are under 50, your physician may recommend at-home testing before scheduling a colonoscopy. This approach lets you complete the test without a day of prior colon preparation. However, it’s essential to note that these tests may overlook some polyps and cancers.
2. Stool DNA Test: Advances in at-home stool testing, such as Cologuard, have made it easier to conduct Fecal Immunochemical Tests (FIT). This simple test checks for blood and genetic changes without requiring extensive dietary changes.
3. Guaiac-based Fecal Occult Blood Test (gFBOT): Another home test prescribed by your doctor, gFBOT identifies hidden blood in the stool. If blood is detected, follow-up with a colonoscopy is typically necessary.

Screening at Healthcare Facilities

Screening procedures conducted in medical facilities are often the most accurate and valuable in colorectal cancer detection, allowing for the immediate removal of any suspicious polyps.

• Standard Colonoscopy: In this procedure, a colonoscope provides detailed images of your colon and allows for tissue removal if abnormalities are found. Proper preparation and sedation are necessary for successful outcomes, and studies show that regular colonoscopies can significantly reduce colorectal cancer mortality rates.
• Virtual Colonoscopy: Utilizing CT imaging to view your colon, this test usually does not require sedation but does involve bowel preparation. If potential issues arise, a standard colonoscopy may follow for confirmation.

When Should You Be Screened for Colorectal Cancer?

The American Cancer Society (ACS) has recently lowered the recommended screening age from 50 to 45 due to rising colorectal cancer rates among younger adults. Contributing factors may include dietary choices, physical inactivity, and obesity.
Recommended screening frequencies vary based on risk levels:

• Average Risk: Adults with no family history of colorectal cancer should undergo screenings every ten years.
• High Risk: Those with a family history, previous inflammatory diseases, or prior radiation exposure to the pelvic area should start screenings earlier and have them more frequently.

Like many cancers, various factors influence your risk of developing colorectal cancer—some of which are controllable and others that are not. While no one can predict with certainty if or when colorectal cancer will arise, educating yourself about these risk factors can empower you to take proactive measures to reduce your likelihood of diagnosis.

By staying informed and proactive, you can play an essential role in your health journey and work towards minimizing your risk of colorectal cancer. At El Portal Comprehensive Cancer Centers, we are here to support you with expertise and compassion every step of the way.

Following your initial consultation with the El Portal team, where your treatment plan is outlined and questions are answered, you’ll be scheduled for a chemotherapy education class. This class will give you essential information about what to anticipate during your treatments, including the duration of appointments, the procedures involved, and resources for addressing questions or side effects after hours.

During this class, you will also meet with a dedicated Patient Financial Counselor who will discuss treatment costs, insurance pre-authorization, and any financial concerns you may have. Once your insurance authorizes your treatment, our office staff will contact you to schedule your first chemotherapy session.

Preparing for Your First Chemotherapy Appointment

Your care team will provide specific instructions for preparing for your first treatment, but in general, preparation is minimal. Drinking plenty of water the day before treatment is recommended, and it is advisable to eat a light meal prior to your appointment. Packing a snack may also help alleviate potential nausea. It’s a good idea to have someone drive you to and from your appointment in case you experience fatigue or nausea afterward.

During your first visit, you will be weighed and have your vital signs checked to ensure it is safe to proceed with chemotherapy. An oncology nurse will insert an IV into your hand or arm, or connect an IV line to your pre-implanted port, if applicable. The chemotherapy drugs will be administered through the IV in a slow, continuous manner. As you receive treatment, you can relax in one of our spacious, light-filled treatment bays equipped with reclining chairs and WiFi access.

Each session may require several hours, so bringing a book or something to watch can make the time more enjoyable. Snacks and water are permitted, and you can make use of the restroom as needed throughout the treatment.

When you’re referred to EPCCC, your medical oncologist and a team of cancer specialists will create a personalized treatment plan tailored to your specific circumstances, considering factors such as:

• Type and grade of your cancer
• Size and location of your tumor
• Sensitivity of surrounding tissues
• Genetic factors
• Family medical history
• Your age, overall health, and previous medical history
• Your treatment goals and preferences

What to Expect During Chemotherapy Treatments

After your initial meeting with your cancer care team to discuss your treatment plan and address any questions, you will be scheduled to attend a chemotherapy education class at El Portal Comprehensive Cancer Centers. This session will provide valuable insights into what you can anticipate from chemotherapy treatment. You will also have the opportunity to meet privately with one of our dedicated cancer financial counselors to discuss treatment costs, insurance coverage, and potential financial assistance.

Your regular chemotherapy treatments will vary based on the specific type of therapy prescribed. Some chemotherapy drugs are given via injection, which is quick, while most are delivered through intravenous infusion, allowing the medication to enter your veins in a slow, continuous manner.

One of the most frequently reported side effects among cancer patients is fatigue. This deep-seated tiredness—often referred to as cancer-related fatigue—can differ significantly from the fatigue experienced by healthy individuals. It can manifest suddenly or gradually, and may not improve with rest. In some cases, fatigue may be compounded by other factors such as anemia and pain. The encouraging news is that this fatigue typically resolves within weeks following the conclusion of treatment.

While side effects will vary by cancer type and individual patient responses, not everyone will experience the same issues. It’s essential to approach this variability with mindfulness and not to expend excessive energy worrying about potential side effects.

Chemotherapy side effects may include:

• Mental fog, often described as “chemo brain,” leading to forgetfulness and difficulty concentrating
• Hair loss
• Easy bruising or bleeding
• Increased susceptibility to infections (bacterial, viral, or fungal)
• Anemia (low red blood cell count)
• Nausea and vomiting
• Loss of appetite
• Constipation and diarrhea
• Pain
• Oral health issues, such as dry mouth, sores, and difficulty swallowing
• Nerve and muscle concerns, including numbness and weakness
• Changes to skin and nails, such as dryness and cracking
• Altered urinary characteristics, affecting color and smell
• Weight loss
• Changes in memory and concentration
• Mood fluctuations
• Alterations in libido and sexual function
• Potential fertility challenges
• Heart-related concerns

In certain cases, chemotherapy may be the sole treatment required. However, it is frequently used in conjunction with other therapies, such as surgery or radiation therapy, to maximize chances of success.

• Neoadjuvant Chemotherapy: Administered before surgery to shrink tumors or halt cancer spread, making surgical procedures less invasive and more effective.
• Concurrent Treatment: Involving chemotherapy or immunotherapy given simultaneously with radiation therapy.
• Adjuvant Chemotherapy: Given after surgery to eliminate any remaining cancer cells, aimed at reducing recurrence risk.

Who Will Oversee Your Chemotherapy?

Your treatment will be overseen by a medical oncologist, a specialist who evaluates your cancer diagnosis and all available treatment options, creating a personalized plan tailored to your needs. As the “quarterback” of your care team at El Portal Comprehensive Cancer Centers, your oncologist will determine chemotherapy’s appropriateness based on several factors, including tumor type, stage, size, and personal considerations.

Your oncologist works alongside a diverse team of healthcare professionals, including radiation oncologists and surgeons, to coordinate your overall care seamlessly. During treatment sessions, a specially trained oncology nurse will administer chemotherapy, monitor your health, address your questions, and assist you in managing any side effects.

Adopting a healthy lifestyle during cancer treatment can help mitigate some side effects and improve your overall well-being. Here are several strategies to consider for managing chemotherapy side effects:

1. Prioritize Rest: Cancer treatment can be exhausting. Make sure to get ample rest, delegate tasks when necessary, and don’t hesitate to ask for help.
2. Stay Active When Possible: While rest is essential, gentle physical activity can enhance energy levels, improve circulation, reduce stress, and maintain muscle strength. Discuss suitable activities with your healthcare provider to find what works best for you.
3. Communicate About Medications: Some medications can interact negatively with cancer treatments. Inform your care team about all the medications you’re taking, including over-the-counter drugs, supplements, and vitamins.
4. Care for Your Skin: If you experience dryness or irritation from treatment, use gentle skincare products. Warm baths with baby oil and fragrance-free lotions can provide relief. Protect your skin from extreme temperatures and stay hydrated.
5. Recognize Your Emotions: The emotional toll of cancer treatment is significant. Feelings of anxiety, anger, sadness, or isolation are common. Engaging with support groups, whether in-person or online, can provide valuable connection and understanding. At El Portal Comprehensive Cancer Centers (EPCCC), we offer resources to help you cope with the emotional aspects of treatment, including support groups and access to licensed clinical oncology social workers. If you find your feelings overwhelming, be sure to discuss them with your care team.

Thanks to recent developments in treatment, many patients find that the severity of chemotherapy side effects has diminished over the years. New medications are also available to help manage side effects, but occasionally, these medications may bring their own challenges.

In certain cases, side effects may signal more serious complications. If you experience any of the following worsening symptoms, please reach out to your care team at EPCCC for guidance (unless experiencing a life-threatening emergency). Our board-certified medical oncologists and specially trained nurses are well-equipped to evaluate your symptoms and recommend appropriate interventions.

If you encounter any of the following issues, our medical professionals are available 24/7 to assist:

• Fever of 100.4°F (38°C) or higher
• Unexplained bruising or bleeding
• Severe rashes or itching
• Swelling in the mouth or throat, along with mouth sores or trouble swallowing
• Swelling in the neck, shoulder, arms, or legs, especially if asymmetrical
• Intense chills
• Unmanaged pain at injection or catheter sites
• Unusual pain, including severe headaches
• Difficulty breathing (immediate emergency care is needed)
• Persistent diarrhea or vomiting
• Blood in stool or urine
• Severe fatigue
• Burning sensation during urination, with lower back pain (potential UTI)
• Productive cough with colored sputum
• Unresolved diarrhea, constipation, nausea, or vomiting
• Dizziness or lightheaded
• Numbness, tingling (feeling of pins and needles) of hands and/or feet

Anemia is the most prevalent benign blood disorder, impacting more than 3 million Americans, according to the National Heart, Lung, and Blood Institute. Anemia occurs when there is a deficiency of red blood cells or hemoglobin in the blood.

Common Symptoms:

• Weakness
• Shortness of breath
• Dizziness
• Pale skin

Anemia can particularly affect women during pregnancy or their childbearing years due to increased iron demands.

Causes of Anemia:

1. Iron Deficiency Anemia: The most common type, usually caused by blood loss from heavy menstrual cycles or gastrointestinal issues, or from inadequate dietary iron. Treatment typically involves iron supplementation, either orally or intravenously.
2. Aplastic Anemia: A rare condition where the bone marrow fails to produce enough blood cells. Causes may include exposure to toxins, medications, or autoimmune disorders. Diagnosis often requires a bone marrow biopsy. Treatment may include immunosuppressive therapies or bone marrow transplantation.
3. Hemolytic Anemia: Occurs when red blood cells are destroyed faster than they can be produced. Causes range from infections to autoimmune disorders, with treatment addressing underlying causes and sometimes using corticosteroids.

Anemia Treatment depends on its cause, severity, and the individual’s overall health. Here are some common treatment options:

1. Dietary Changes: Increasing intake of iron-rich foods (e.g., red meat, beans, lentils, spinach) and foods high in vitamin B12 and folate (e.g., dairy, eggs, leafy greens).

2. Iron Supplements: Oral or intravenous iron supplements may be prescribed, especially for iron-deficiency anemia.

3. Vitamin Supplements: If the anemia is due to vitamin B12 or folate deficiency, supplements or injections may be recommended.

4. Medications: For anemia related to chronic diseases, medications such as erythropoietin-stimulating agents may be used to stimulate red blood cell production.

5. Blood Transfusions: In severe cases, a transfusion of red blood cells may be necessary to quickly increase hemoglobin levels.

6. Managing Underlying Conditions: Treating the underlying cause of anemia, such as chronic kidney disease, can alleviate symptoms.

7. Bone Marrow Stimulants: In certain cases, treatments that stimulate the bone marrow to produce more red blood cells may be indicated.

It’s essential to consult a healthcare provider for a proper diagnosis and treatment plan tailored to the individual’s specific condition and needs.T

Bleeding disorders are conditions in which the blood does not clot properly, leading to excessive bleeding. At El Portal Comprehensive Cancer Centers, our experts specialize in treating various bleeding disorders, including hemophilia and von Willebrand disease.

• Hemophilia: A genetic disorder mainly affecting males, characterized by excessive bleeding from minor injuries. Modern treatments use synthetic concentrated clotting factors administered intravenously, along with vasopressin to manage bleeding.
• Von Willebrand Disease : An inherited condition caused by a deficiency in a protein essential for blood clotting. Treatment focuses on preventing and managing bleeding episodes, often using synthetic hormones similar to vasopressin.

Treatment options for bleeding disorders like hemophilia and von Willebrand disease (vWD) focus on managing and preventing bleeding episodes. Here are common approaches for each:

Hemophilia:

1. Factor Replacement Therapy:
   • Prophylactic Treatment: Regular infusions of clotting factor concentrates (Factor VIII for Hemophilia A and Factor IX for Hemophilia B) to prevent bleeding episodes.
   • On-Demand Treatment: Administering clotting factors when a bleeding episode occurs.
2. Desmopressin (DDAVP):
   • Used for mild cases of Hemophilia A to stimulate the release of stored Factor VIII from blood vessel lining.
3. Gene Therapy:
   • Investigational treatments aim to provide a functional copy of the missing clotting factor gene, potentially offering a long-term solution.
4. Supportive Treatments:
   • Pain management and rehabilitation for joint health, along with lifestyle adjustments to prevent injury.

von Willebrand Disease (vWD):

1. Desmopressin (DDAVP):
   • The first line of treatment for many with type 1 vWD and some with type 2, as it helps increase von Willebrand factor (vWF) and Factor VIII levels in the blood.
2. Factor Replacement Therapy:
   • Concentrates containing von Willebrand factor and Factor VIII may be used for severe cases or during surgery.
3. Antifibrinolytic Agents:
   • Medications like tranexamic acid may be used to help prevent bleeding during dental procedures or other situations.
4. Avoiding Medications That Affect Clotting:
   • Recommendations to avoid aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) that can increase bleeding risk.
5. Lifestyle and Preventive Measures:
   • Education on avoiding injuries and managing heavy menstrual bleeding in women.

It’s crucial for individuals with bleeding disorders to work closely with a healthcare provider or a specialized hematologist to tailor treatment plans based on their specific needs and to manage their condition effectively.

Treatment options for blood clotting disorders aim to prevent clots from forming, manage existing clots, and reduce the risk of complications. Here are some common approaches based on different types of clotting disorders:

1. Anticoagulant Medications:

– Warfarin (Coumadin): A vitamin K antagonist used to prevent the formation of new clots and to keep existing clots from growing.

– Direct Oral Anticoagulants (DOACs): Medications such as apixaban (Eliquis), rivaroxaban (Xarelto), and dabigatran (Pradaxa) that directly inhibit specific clotting factors.

2. Antiplatelet Medications:

– Aspirin: Often used to prevent clot formation in arteries, particularly in individuals with a history of heart attacks or stroke.

– Clopidogrel (Plavix): Another antiplatelet medication that may be used alone or in combination with aspirin.

3. Thrombolytics:

– Clot Busters: Medications like alteplase (Activase) are used in emergency situations to dissolve large clots quickly, such as those causing strokes or pulmonary embolisms.

4. Compression Therapy:

– Compression Stockings: Used to improve blood flow and reduce swelling in individuals with venous thromboembolism (VTE) or chronic venous insufficiency.

5. Surgery:

– Thrombectomy: Surgical removal of a blood clot may be necessary in severe cases.

– Placement of Inferior Vena Cava (IVC) Filters: A filter may be placed in the IVC to catch clots that may travel from the legs to the lungs, particularly in patients with recurrent clots.

6. Lifestyle and Preventive Measures:

– Dietary Changes: Monitoring vitamin K intake (for patients on warfarin) and maintaining a balanced diet.

– Regular Exercise: Encouraging activity that enhances blood flow, while ensuring safety to avoid injury.

– Hydration: Staying well-hydrated to help maintain proper blood viscosity.

7. Management of Underlying Conditions:

Treating conditions that contribute to clotting disorders, such as atrial fibrillation, hormonal imbalances, or certain types of cancer.

Genetic Counseling:

For hereditary clotting disorders, genetic counseling may be beneficial for affected individuals and their families to understand risks and management strategies.

It’s essential for individuals with blood clotting disorders to work closely with a healthcare provider to develop a tailored treatment plan and to monitor their condition effectively. Regular follow-up and education about the disorder are also crucial parts of effective management.

Myelodysplastic syndromes represent a group of disorders where the bone marrow fails to produce healthy blood cells, leading to insufficient white blood cells, red blood cells, and platelets. Patients with MDS may experience:

• Increased risk of infections due to low white blood cell counts.
• Fatigue and shortness of breath from anemia.
• Excessive bleeding due to low platelet levels.

Treatment options may include blood transfusions, medications to stimulate blood cell production, or immune-suppressive therapies.

Infusions are used to treat a wide range of medical conditions, including:

• Cancer: Chemotherapy agents, targeted therapies, and immunotherapies are often administered via infusion to treat various cancers such as breast, lung, and leukemia.
• Autoimmune Disorders: Conditions like rheumatoid arthritis, lupus, and multiple sclerosis may be treated with biological agents delivered through infusions to help regulate the immune system.
• Infections: Severe infections might require antibiotics delivered through infusion for immediate and effective treatment.
• Nutritional Support: Patients unable to eat or absorb nutrients through the gastrointestinal tract may receive nutritional solutions (Total Parenteral Nutrition, TPN) via infusion.
• Pain Management: For chronic pain conditions, infusions of medications such as opioids or analgesics may provide relief.
• Hydration and Electrolyte Replacement: IV fluids are commonly used for rehydration in patients with severe dehydration or electrolyte imbalances.

While infusion therapy is generally safe, certain factors may increase the risk of complications, including:

• Allergies:Some patients may have allergic reactions to medications being infused.
• Infection Risk:The insertion of IV lines can lead to infections if not performed under sterile conditions.
• Pre-existing Conditions:Patients with compromised immune systems, heart conditions, or kidney issues may face additional risks.
• Substance Interactions:Patients should disclose all medications, supplements, and herbal products they are taking, as interactions can occur.

Timing of Treatments: The timing of infusion treatments varies based on the condition being treated:

• Cancer Patients: Infusion schedules can be based on specific chemotherapy regimens, often occurring every few weeks or as prescribed by an oncologist.
• Autoimmune Disorders: Infusions may be scheduled monthly or as part of a broader treatment plan based on symptoms and disease activity.
• Acute Conditions: Infusions for infections or severe hydration may occur as needed, often in a hospital setting.

Side effects of infusion therapy can vary depending on the type of medication and individual patient factors. Common side effects include:

• Infusion Reactions:Fever, chills, or rashes occurring during or shortly after the infusion.
• Nausea and Vomiting:Particularly common with chemotherapy agents.
• Fatigue:Many patients experience tiredness following infusion sessions.
• Infections:Risks associated with the use of IV lines.
• Local Reactions: Bruising, swelling, or inflammation at the injection site.

The success rate of infusion therapy depends on several factors, including:

• Type of Condition: Certain cancer treatments administered via infusion can have high cure rates, especially when applied at early stages.
• Individual Response: How a patient responds to the specific medication influences effectiveness.
• Comprehensive Treatment Plan: Optimizing infusion therapy as part of a broader treatment strategy (including surgery, radiotherapy, etc.) can enhance success rates.

For example:

• Chemotherapy: May lead to significant tumor shrinkage or remission in many cancer patients.
• Biologics for Autoimmunity: Often result in substantial improvements in symptoms and quality of life for patients with autoimmune diseases.

During radiation therapy, a team led by a radiation oncologist—a specialist in this treatment—will carefully plan and supervise your treatment. Each session typically involves directing high-energy radiation toward the cancer cells using specialized equipment. This targeted exposure fractures the DNA within the cancer cells, making it difficult for them to grow and multiply. While healthy surrounding cells may also be exposed to some radiation, most can recover and continue functioning normally, whereas cancer cells generally cannot.

At El Portal Comprehensive Cancer Centers, we utilize the latest and most advanced radiation technologies to minimize exposure to healthy cells. Our accredited equipment undergoes daily checks to ensure the highest level of precision in treatment.

There are two main categories of radiation therapy:

External Beam Radiation Therapy

This method delivers radiation from a machine outside the body, directing beams specifically at the cancer site. The equipment does not physically contact the body and can be adjusted to deliver radiation from multiple angles. Treatment typically occurs five days a week for a duration ranging from 1 to 10 weeks.

Technologies may include:

• TrueBeam Radiotherapy:Offers advanced options tailored to your specific anatomy and cancer type.
• Image-guided Radiation Therapy (IGRT):Uses imaging (such as CT or ultrasound) to accurately direct radiation.
• Intensity-modulated Radiation Therapy (IMRT):Shapes radiation beams around tumors while sparing surrounding healthy organs.
• Stereotactic Radiosurgery (SRS):A non-invasive approach treating irregularly shaped tumors, particularly in the brain.
• Stereotactic Body Radiation Therapy (SBRT):Similar to SRS, but designed for tumors outside the skull.
• Hypofractionated Radiation Therapy:A specialized technique for breast cancer treatment, depending on individual patient factors.

Internal Radiation Therapy

Internal radiation therapy, or brachytherapy, involves placing radioactive material directly inside or near the tumor. This may include various implants such as pellets, seeds, or tubes, which are inserted using minimally invasive methods.

At El Portal Comprehensive Cancer Centers, we offer:

• High-Dose Rate (HDR) Brachytherapy:Often utilized for uterine or cervical cancers, this approach involves placing radioactive material for short durations multiple times.
• Selective Internal Radiation Therapy (SIRT):An innovative, non-surgical procedure for liver tumors, delivered via tiny radioactive beads inserted directly into blood vessels leading to the tumor.

After a cancer diagnosis, you will likely be referred to a cancer specialist, such as a surgical oncologist or medical oncologist. Your treatment plan, which may include radiation therapy, is tailored uniquely based on:

• Type and grade of cancer
• Size and location of the tumor
• Sensitivity of surrounding tissue
• Genetic components
• Family history
• Age, overall health, and medical background
• Personal treatment goals and preferences

Your doctor will also consider whether you have previously received radiation to that area, as each body part has a safe lifetime dose of radiation. The decision to proceed with radiation for recurrence depends on the location of the tumor, cancer type, and past radiation exposure.

Radiation therapy may be recommended as a standalone treatment or in conjunction with surgeries, chemotherapy, or immunotherapy. At El Portal Comprehensive Cancer Centers, we typically can schedule your first appointment within two days of your referral.

Radiation therapy demands a high degree of skill, precision, and experience. Selecting a provider with state-of-the-art technology and strict protocols ensuring equipment accuracy is essential.

At El Portal Comprehensive Cancer Centers, we have been delivering high-quality radiation therapy for patients across California for over 15 years. Our board-certified radiation oncologists bring expertise and compassion to your care.

Key factors to consider include:

• Technology:Choose a center equipped with the most advanced equipment for optimal treatment.
• Experience:Our dedicated team ensures patients receive knowledgeable and compassionate care.
• Affordability:As the largest community-based cancer center, we strive to provide services in a cost-effective