Your Strength. Our Knowledge and Experience.

When faced with a cancer diagnosis, the journey ahead is profoundly influenced by the support of the best doctors, options, and support team who work with you.

Mother with her two daughters
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We see you. All of you.

At El Portal Comprehensive Cancer Centers (EPCC), you will benefit from a dedicated team of doctors, nurses, and treatment professionals united by one common goal: an unwavering commitment to your health and well-being. 

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Your fight is personal for us.

We will deliver personalized, world-class care infused with compassion and kindness. Here, you can trust that you will receive cutting-edge treatment along with the highest quality of care.

Compassionate care is premiere at El Portal Cancer Center in the Central Valley of California
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Choose El Portal Comprehensive Cancer Centers as your trusted partner in this journey.

We are a multidisciplinary practice in Central California dedicated to providing care for patients with cancer and diseases of the blood.

Infusion Services

Our Infusion Center prioritizes your health with a commitment to providing excellent care. The first step towards better health is just a drip away, ensuring that you receive the support and treatment you need to enhance your well-being. Learn More information about Infusion Therapy.

Hematology/Oncology

Chemotherapy, Targeted Therapy, Immunotherapy, Iron (Infed, Venofer, Injectafer,  Feraheme, Monoferric), Therapeautic Phlebotomy

Neurology

IVIG, Tysabri, Solu-Medrol, Ocrevus, Leqembi,  Briumvi, Kisunla

IV Infusion/Injectable

Normal Saline (IV Fluids), IV Antibiotics, Prolia, Reclast, Evenity, Dupixent, & Xolair

Rheumatology

Rituxan, Actemra, & Orencia

Gastroenterology

Remicade, Entyvio, Stelera, Cimzia, & Skyryzi

Wellness

Vitamin C infusions, Myers Cocktail infusions,   Glutathione infusions, NAD+ Booster Infusions,  Inflammation and Detoxifying Treatments, Immune  Boosting Drip Treatments, Skin Rejuvenation   Infusions, as well as B12, Lipo-B, and NAD+   Injections

What our patients have to say...

april B. profile pictureapril B.
21:29 22 May 25
I feel fortunate to have been referred to Dr.M as my hematologist. He's been very attentive, thorough, and caring. He is a great Doctor who cares about his patients. Thank you so much Dr. M for caring, as well as to his staff who've been professional and kind also.
Stella Z. profile pictureStella Z.
15:40 19 May 25
Amazing place, front desk and doctors are friendly.
Neveah profile pictureNeveah
18:55 01 May 25
i love it here the ladies here are so nice and have a gentle hand when it comes to the needle. i feel comfortable and unjudged here and enjoy the time i spend here getting to talk to everyone.
Jaimie C. profile pictureJaimie C.
22:43 30 Apr 25
Love every single one of the girls who work in the infusion room. They do such a great job and always make sure we are comfortable and taken care of.
Natasha G. profile pictureNatasha G.
16:32 24 Apr 25
I can’t say enough great things about this place! From the moment I walked in, the staff made me feel more like family than a patient. Everyone is incredibly friendly, professional, and truly goes above and beyond to make sure you're comfortable. They explain every step of the process in detail, which really helps put your mind at ease.

The iron infusion room is spotless—super clean and sanitized, which I really appreciated. Danica and her amazing team are simply the best. Their care, compassion, and warmth made such a difference during my treatment. Once I’m done, I know I’ll truly miss them.

Thank you to the entire staff for making this experience as smooth and comforting as possible. Highly recommend!
Patricia L. profile picturePatricia L.
21:35 21 Apr 25
Thank you Isabel MA for your amazing help, best communication and treatment I received here much lovely service here
Mychelle C. profile pictureMychelle C.
19:00 26 Mar 25
Danika is awesome!!! She always makes sure to make sure I am as comfortable as possible!! The girls are all amazing!!

Share Your Journey with Us!

At El Portal Comprehensive Cancer Centers (EPCC), we believe that every story matters. Your experiences, struggles, and victories can inspire others who are navigating their own cancer journeys. By sharing your story, you not only help build a supportive community but also empower others to find hope and strength.

Working together to explore treatment options and to create a personalized plan based on your diagnosis and lifestyle.

News | Articles | EVENTS

Newly Diagnosed? Here’s What You Should Do Next.

Receiving a prostate cancer diagnosis can be overwhelming, and there are important decisions to be made. It’s natural to have questions, and we are here to help you navigate your options and understand what lies ahead. You’ll learn about your cancer care team and what to expect as you embark on this journey.

What Type of Doctor Should You See First After a Prostate Cancer Diagnosis?

Typically, a urologist will perform the biopsy that confirms the presence of prostate cancer and assesses its aggressiveness. Following this initial diagnosis, we recommend scheduling a consultation with an oncologist. Our dedicated oncologists are well-versed in the latest treatment options, ensuring you receive therapies tailored specifically for you.

Understanding the Extent of Prostate Cancer

Your oncologist will help you understand the growth pattern of the cancer and how it may evolve moving forward. The biopsy results, combined with other diagnostic tests, will provide the necessary information to determine both the stage and grade of your prostate cancer.

Staging Prostate Cancer

Using the results from your biopsy and additional diagnostic tests, your oncologist will ascertain the stage of your prostate cancer. Further imaging or scans may be required to identify whether cancer cells have extended beyond the prostate.

Gleason Score and Grading

The Gleason score, included in your biopsy report, indicates how much the cancer cells have altered in various parts of the prostate. This grading aids in determining whether immediate treatment is necessary.

The Gleason score is a system used to grade prostate cancer based on how aggressive and likely it is to spread. It is determined by examining cancer cells under a microscope and assigning them a score from 1 to 5.

Grading:
1-2: Well-differentiated, least aggressive
3-4: Moderately differentiated
5: Poorly differentiated, most aggressive

Gleason scores are subject to interpretation and may vary slightly between pathologists. It is important to discuss your Gleason score with your healthcare provider to understand its implications and treatment options.

Preparing for Your First Oncology Appointment

Preparing for Your First Oncology Appointment

Your first oncology appointment is essential for gathering important information, but it can be overwhelming. We suggest bringing a notebook or using your smartphone to take notes during the appointment. This will help you keep track of important details and any questions that arise.

We strongly encourage you to bring a friend or loved one for support. They can take notes, ask questions that might be on your mind, and provide reassurance.

Additionally, please bring your health records, including any prostate cancer test results, recent imaging scans, your insurance card, and a list of medications or supplements you’re currently taking.

Questions to Discuss with Your Oncologist

  • How soon do I need to decide on a treatment plan?
  • If “watchful waiting” is recommended, how often should I return for follow-up testing?
  • What treatment options do you suggest when the time comes to proceed?
  • What should I expect during future appointments?
  • Are there lifestyle changes (in diet, exercise, rest, or stress management) I should consider?
  • How should I manage any symptoms affecting my daily life?
  • Are there any activities I should avoid or incorporate into my routine?
  • Can I take nutritional supplements or vitamins to support my prostate health?
  • Should my family and I consider genetic testing to check for hereditary risk?
  • What supportive care resources are available through your practice or community organizations?

The Importance of Seeking Second Opinions

Feeling confident about your prostate cancer diagnosis and treatment plan is vital, even if it begins with watchful waiting. Many patients choose to seek a second opinion, and our oncologists are completely supportive of this decision. Insurance coverage for second opinions is often available, so we recommend contacting your insurance provider to verify your benefits before scheduling an appointment.

You Are Not Alone on Your Prostate Cancer Journey

At El Portal Comprehensive Cancer Centers, we are committed to supporting you throughout your entire journey. With convenient locations across Central California, we are here to offer you compassionate care and guidance every step of the way. Together, we will navigate this path to achieve the best possible outcome for your health and well-being.

Dr. Alireza Mahmoudieh, M.D.

Dr. Mahmoudieh has been a vital member of El Portal Comprehensive Cancer Centers since 2008, bringing over a decade of dedicated experience to patient care. Before joining our team, he served as the Director of the Prostate Brachytherapy Program at Kaiser Permanente in Sacramento and Roseville, demonstrating his leadership in advanced cancer treatments.

He earned his medical degree from the Albert Szent-Györgyi School of Medicine in Szeged, Hungary, in 1996. With a strong interest in treating head, neck, and breast cancers, Dr. Mahmoudieh specializes in cutting-edge techniques such as Image-Guided Radiation Therapy (IGRT) and Intensity-Modulated Radiation Therapy (IMRT). His expertise extends to treating cancers of the head and neck, lung, gastrointestinal tract, and prostate.

A committed professional, Dr. Mahmoudieh is a member of the American Society for Therapeutic Radiology and Oncology (ASTRO), reflecting his engagement with ongoing developments in cancer treatment and research. His compassionate approach and advanced skill set ensure that each patient receives personalized, state-of-the-art care.

Outside of his professional life, Dr. Mahmoudieh enjoys traveling with his son and daughter, as well as reading and playing racquetball, embracing a balanced and active lifestyle. His dedication to both his patients and his personal passions makes him a trusted partner in your journey toward health.

Dr. Osman Elhanafy, Ph.D

Dr. Elhanafy is a highly respected Associate Professor of Medical Physics and serves as the Chief Medical Physicist at El Portal Comprehensive Cancer Centers since July 2013. He earned his Ph.D. in Medical Physics from the University of Wisconsin, Madison—where he began his foundational training and completed his thesis—in 2013, building on his initial joining of the university in 1999.

 With specialized training in advanced radiation oncology techniques—such as Intensity-Modulated Radiation Therapy (IMRT), High-Dose Rate Brachytherapy (HDR), Stereotactic Radiosurgery (SRS), Total Body Irradiation (TBI), Quality Assurance, and Radiobiology—Dr. Elhanafy brings a wealth of expertise to patient care. His dedication to the field is evident through numerous published research articles, as well as awards recognizing his leadership in organizing conferences, training sessions, lectures, and workshops.

Beyond his impressive credentials, Dr. Elhanafy is deeply committed to advancing medical physics and ensuring the best possible outcomes for his patients. His compassionate approach, combined with his extensive knowledge, makes him a trusted partner in your cancer care journey.

Outside of his professional pursuits, he values spending quality time with his family, reflecting his genuine care and balance in life.

Dr. Harish Ahuja, M.D.

Dr. Ahuja is a distinguished, board-certified Medical Oncologist with extensive training in medical hematology. He has refined his expertise at renowned institutions such as Tata Memorial Hospital, UCLA School of Medicine, and Roswell Park, under the mentorship of esteemed hematologists including Dr. S.H. Advani, Dr. Michael Caligiuri, and Dr. M.J. Cline.

With over 25 years of experience in both hematology and oncology, Dr. Ahuja offers a deep well of knowledge and a compassionate approach to patient care at El Portal Cancer Center. His dedication to advancing the field is reflected through active membership in prestigious professional organizations, including the American Society of Hematology, the American Society of Clinical Oncology, the European Society of Medical Oncology, and the Indian Society of Medical and Pediatric Oncology.

A passionate researcher, Dr. Ahuja has contributed significantly to ongoing scientific advancements—serving on the NRG Breast Committee and the Rare Subtype Committee, and acting as Principal Investigator for the “CROWN” NCORP study. His commitment to clinical excellence and groundbreaking research underscores his dedication to improving outcomes for his patients.

Outside of his professional pursuits, Dr. Ahuja values spending quality time with his family, and enjoys hiking and traveling, embracing life outside the clinic with the same dedication he brings to his medical practice. His compassionate nature and extensive experience make him a trusted partner in your cancer care journey.

Dr. Sidney Crain, M.D.

Dr. Crain is a highly experienced and board-certified Medical Oncologist and Hematologist with over 45 years of dedicated service in the medical field. Throughout his distinguished career, he has established himself as a leading expert in the diagnosis, treatment, and prevention of various cancers and blood disorders.

He earned his medical degree from the University of Illinois College of Medicine in 1977 and is actively affiliated with esteemed institutions, including Adventist Health St. Helena. Dr. Crain’s extensive experience spans a broad range of conditions, including small intestine and colorectal cancers, breast cancer, prostate cancer, anemia, leukemia, and lymphoma.

Beyond his clinical expertise, Dr. Crain is deeply committed to advancing medical research and improving patient care. His approach to treatment is rooted in compassion and a thorough understanding of complex medical conditions, ensuring each patient receives personalized, comprehensive care.

Recognized for his empathetic nature and unwavering dedication, Dr. Crain strives to achieve the best possible outcomes for his patients and foster a trusting, supportive environment. His lifelong commitment to the fields of oncology and hematology reflects his passion for making a meaningful difference in his patients’ lives.

Michael Kangas

Michael Kangas serves as the Director of Oncology and Diagnostic Imaging, where he spearheads initiatives that enhance revenue, profitability, productivity, and patient satisfaction within an underserved area. His leadership is instrumental in developing and guiding a highly skilled team of healthcare professionals across multiple clinics, providing comprehensive cancer care and diagnostic imaging services utilizing the most advanced technology. Michael’s commitment is rooted in delivering personalized, high-quality care to each patient, ensuring they receive the support they need throughout their journey.

With extensive expertise in Health Information Management, Electronic Medical Records (EMR), Radiation Therapy, Radiation Oncology, Clinical Operations, Healthcare Compliance, and Regulatory Standards, Michael ensures that all services meet the highest industry standards. He also focuses on monitoring performance, healthcare marketing, and supervisory skills to foster a collaborative, efficient, and patient-centered environment.

In addition to his clinical leadership, Michael actively volunteers with the Merced Cancer Society Foundation as its Executive Director. In this role, he oversees key operational and administrative functions to advance the foundation’s mission of positively impacting residents in the Central Valley. His efforts include community outreach, organizing fundraising events, and leading initiatives to expand the foundation’s support and resources for local cancer patients.

Michael’s dedication to improving healthcare and strengthening community ties highlights his unwavering commitment to healing, hope, and making a meaningful difference in the lives of those he serves.

Paul Mosher

Paul I. Mosher is a highly accomplished business professional with extensive experience in healthcare management, medical device sales, and community service. Currently, he proudly serves as the Physician Liaison and Business Development Coordinator at El Portal Comprehensive Cancer Center. In this role, Paul collaborates closely with our dedicated medical team to facilitate patient-centered care, foster strong relationships with our physicians, and support the center’s mission of providing the highest quality cancer treatment.

With expertise in business development, leadership, relationship management, and healthcare technology, Paul is a dedicated and effective communicator committed to exceptional service and compassionate support. His collaborative approach helps ensure that patients receive not only cutting-edge treatment but also personalized care rooted in trust and understanding. Additionally, Paul brings ten years of non-profit experience to our board of directors, furthering his devotion to community health and service.

Paul holds a Bachelor of Business in Business Marketing from Boise State University. He is actively involved in his community, volunteering with various Merced non-profits and churches. Outside of work, Paul enjoys spending quality time with his family and playing golf whenever he can.