Your Strength. Our Knowledge and Experience.

When faced with a cancer diagnosis, the journey ahead is profoundly influenced by the support of the best doctors, options, and support team who work with you.

Mother with her two daughters
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We see you. All of you.

At El Portal Comprehensive Cancer Centers (EPCC), you will benefit from a dedicated team of doctors, nurses, and treatment professionals united by one common goal: an unwavering commitment to your health and well-being. 

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Your fight is personal for us.

We will deliver personalized, world-class care infused with compassion and kindness. Here, you can trust that you will receive cutting-edge treatment along with the highest quality of care.

Compassionate care is premiere at El Portal Cancer Center in the Central Valley of California
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Choose El Portal Comprehensive Cancer Centers as your trusted partner in this journey.

We are a multidisciplinary practice in Central California dedicated to providing care for patients with cancer and diseases of the blood.

Infusion Services

Our Infusion Center prioritizes your health with a commitment to providing excellent care. The first step towards better health is just a drip away, ensuring that you receive the support and treatment you need to enhance your well-being. Learn More information about Infusion Therapy.

Hematology/Oncology

Chemotherapy, Targeted Therapy, Immunotherapy, Iron (Infed, Venofer, Injectafer,  Feraheme, Monoferric), Therapeautic Phlebotomy

Neurology

IVIG, Tysabri, Solu-Medrol, Ocrevus, Leqembi,  Briumvi, Kisunla

IV Infusion/Injectable

Normal Saline (IV Fluids), IV Antibiotics, Prolia, Reclast, Evenity, Dupixent, & Xolair

Rheumatology

Rituxan, Actemra, & Orencia

Gastroenterology

Remicade, Entyvio, Stelera, Cimzia, & Skyryzi

Wellness

Vitamin C infusions, Myers Cocktail infusions,   Glutathione infusions, NAD+ Booster Infusions,  Inflammation and Detoxifying Treatments, Immune  Boosting Drip Treatments, Skin Rejuvenation   Infusions, as well as B12, Lipo-B, and NAD+   Injections

What our patients have to say...

april B. profile pictureapril B.
21:29 22 May 25
I feel fortunate to have been referred to Dr.M as my hematologist. He's been very attentive, thorough, and caring. He is a great Doctor who cares about his patients. Thank you so much Dr. M for caring, as well as to his staff who've been professional and kind also.
Stella Z. profile pictureStella Z.
15:40 19 May 25
Amazing place, front desk and doctors are friendly.
Neveah profile pictureNeveah
18:55 01 May 25
i love it here the ladies here are so nice and have a gentle hand when it comes to the needle. i feel comfortable and unjudged here and enjoy the time i spend here getting to talk to everyone.
Jaimie C. profile pictureJaimie C.
22:43 30 Apr 25
Love every single one of the girls who work in the infusion room. They do such a great job and always make sure we are comfortable and taken care of.
Natasha G. profile pictureNatasha G.
16:32 24 Apr 25
I can’t say enough great things about this place! From the moment I walked in, the staff made me feel more like family than a patient. Everyone is incredibly friendly, professional, and truly goes above and beyond to make sure you're comfortable. They explain every step of the process in detail, which really helps put your mind at ease.

The iron infusion room is spotless—super clean and sanitized, which I really appreciated. Danica and her amazing team are simply the best. Their care, compassion, and warmth made such a difference during my treatment. Once I’m done, I know I’ll truly miss them.

Thank you to the entire staff for making this experience as smooth and comforting as possible. Highly recommend!
Patricia L. profile picturePatricia L.
21:35 21 Apr 25
Thank you Isabel MA for your amazing help, best communication and treatment I received here much lovely service here
Mychelle C. profile pictureMychelle C.
19:00 26 Mar 25
Danika is awesome!!! She always makes sure to make sure I am as comfortable as possible!! The girls are all amazing!!

Share Your Journey with Us!

At El Portal Comprehensive Cancer Centers (EPCC), we believe that every story matters. Your experiences, struggles, and victories can inspire others who are navigating their own cancer journeys. By sharing your story, you not only help build a supportive community but also empower others to find hope and strength.

Working together to explore treatment options and to create a personalized plan based on your diagnosis and lifestyle.

News | Articles | EVENTS

Types of Bladder Cancer

  1. Transitional Cell Carcinoma (Urothelial Carcinoma): The most common type, originating in the bladder’s inner lining.

  2. Squamous Cell Carcinoma: Less common, often linked to irritation and inflammation of the bladder.

  3. Adenocarcinoma: A rare form that develops from glandular cells in the bladder.

  4. Small Cell Carcinoma: A rare and aggressive type that resembles small cell lung cancer.

Bladder Cancer Diagnosis

  1. Medical History and Physical Examination: A healthcare provider will assess symptoms and perform a physical exam.

  2. Urinalysis: A urine test can reveal blood (hematuria) or abnormal cells.

  3. Cystoscopy: A thin tube with a camera is inserted into the bladder to visually inspect for tumors or abnormalities.

  4. Biopsy: If abnormal tissue is found, a biopsy may be conducted during cystoscopy to confirm the presence of cancer.

  5. Imaging Tests: CT scans, MRIs, or ultrasounds may be used to evaluate the extent of the disease.

Bladder Cancer: Signs, Symptoms, and Risks

Signs and Symptoms

  • Blood in Urine (Hematuria): The most common symptom.
  • Frequent Urination: A strong urge to urinate more often than usual.
  • Painful Urination: Discomfort or burning sensation while urinating.
  • Lower Abdominal Pain: Discomfort in the bladder or pelvic area.
  • Back Pain: Pain in the lower back may also occur in advanced stages.

Risk Factors

  1. Smoking: The leading risk factor associated with bladder cancer.
  2. Chemical Exposure: Contact with certain chemicals, especially in industrial settings.
  3. Chronic Irritation: Repeated urinary tract infections or bladder inflammation.
  4. Family History: A genetic predisposition can increase risk.
  5. Age and Gender: More common in older adults and men.

Bladder Cancer: Potential Treatment Options

This information provides a snapshot of bladder cancer, covering essential aspects for better understanding.

  • Surgery:
    Transurethral Resection (TURBT): A common procedure to remove tumors.
    Cystectomy: Removal of part or all of the bladder in advanced cases.
  • Chemotherapy:
    Used to kill cancer cells or prevent them from growing, either before or after surgery.
  • Immunotherapy:
    Treatments that help the immune system recognize and attack cancer cells.
  • Radiation Therapy:
    Can be used in conjunction with other treatments or for patients who cannot undergo surgery.
  • Targeted Therapy:
    Newer drugs target specific characteristics of cancer cells to block their growth.

Difficulty Sleeping / Fatigue

Difficulty Sleeping – Sleep disturbances can occur during treatment, which may exacerbate fatigue. Consider these strategies to improve sleep:

  • Create a calming bedtime routine.
  • Keep your sleeping environment dark, cool, and quiet.
  • Go to bed and wake up at consistent times.
  • Limit screen time before bed and reduce caffeine intake.
  • Discuss melatonin or other sleep aids with your healthcare provider.


Fatigue – Fatigue can be overwhelming and may affect your mental health as well. Strategies for managing fatigue include:

  • Engaging in regular, light exercise to boost energy levels.
  • Practicing yoga or meditation to alleviate emotional stresses.
  • Consulting with a counselor or social worker for additional support.

Hair Loss / Skin Problems

Hair Loss – While hair loss is often associated with cancer treatment, not every patient will experience it. To manage hair loss:

  • Be gentle with your hair care routine and consider head coverings or wigs to boost your confidence.
  • Use cooling caps, if recommended, to possibly reduce hair loss during chemotherapy.
  • Connect with support groups to share experiences and feelings surrounding hair loss.


Skin Problems – Treatments can lead to various skin changes. To care for your skin during treatment:

  • Keep affected areas clean and moisturized with gentle, fragrance-free products.
  • Wear loose-fitting clothing and use sunscreen to protect sensitive skin.

Loss of Appetite / Nausea and Vomiting

Loss of Appetite – Maintaining proper nutrition is vital during treatment. If you experience appetite changes:

  • Opt for smaller, more frequent meals packed with protein.
  • Stay hydrated and ask about anti-nausea medications that can improve your eating experience.
  • Consider discussing dietary changes with a nutritionist.


Nausea and Vomiting – These are common effects of many cancer treatments. To mitigate nausea:

  • Avoid strong scents and stick to bland foods.
  • Maintain hydration, especially with electrolyte drinks if vomiting occurs.
  • Take prescribed anti-nausea medications as directed.

Lymphedema / Managing Pain

Lymphedema – This condition may result from surgery or radiation impacting the lymphatic system. To manage lymphedema:

  • Wear compression garments and consult with a certified lymphedema therapist for specialized care.
  • Regular exercise and gentle stretching can improve lymph fluid drainage.

 

Pain – Managing pain effectively is crucial to your overall well-being. Strategies include:

  • Taking prescribed medications consistently and discussing pain management options with your doctor.
  • Applying heat or ice to areas of discomfort, depending on what provides relief.

Diagnosing Lung Cancer

How is Lung Cancer Diagnosed?

The path to effective treatment begins with an accurate diagnosis of lung cancer. Understanding the tests involved in determining lung cancer type, stage, and whether the disease has spread to other areas of the body is essential.

Lung Cancer Detection and Diagnosis

Early detection is key to successfully treating lung cancer. This is why it is critical for smokers and former smokers to have annual lung screenings, as symptoms often do not manifest until the cancer has reached an advanced stage.

Tests Used for Lung Cancer Diagnosis

A variety of tests help in detecting, diagnosing, and staging lung cancer, as well as in understanding whether the cancer has metastasized to other parts of the body. A biopsy remains the most definitive method for diagnosis, involving the collection of a small tissue sample for laboratory testing. Your doctor will consider several factors when selecting the appropriate diagnostic tests, including the size and location of the suspected cancer, your symptoms, overall health, and prior test results.

Common diagnostic tests include:

  • Chest X-ray:Provides images of the organs and bones in the chest.
  • CT Scan:Offers detailed cross-sectional images of the chest, abdomen, and brain, often with a contrast dye.
  • MRI:Utilizes magnets and radio waves to create detailed images of internal structures.
  • PET Scan:Detects malignant cells by using radioactive glucose, highlighting areas of increased activity.
  • Radionuclide Bone Scan:Identifies cancer cells in the bones through a small injection of radioactive material.


Specific Diagnostic Procedures

Procedures to confirm the diagnosis of lung cancer may include:

  • Fine-Needle Aspiration (FNA) Biopsy:Targets abnormal lung tissue to collect samples for testing.
  • Thoracentesis:Removes fluid to check for cancer cells in the space surrounding the lung.
  • Sputum Cytology:An examination of mucus from the lungs for cancer cells.


Molecular Testing for Non-Small Cell Lung Cancer

Genetic testing is critical for understanding mutations within the cancerous tissue that may respond to targeted therapies. Biomarker testing, such as PD-L1 evaluation, can inform immunotherapy options.

Support for Newly Diagnosed Patients

If you’ve recently received a lung cancer diagnosis, the EPCC team is here to support you every step of the way. We offer access to advanced treatment options and resources designed for you and your loved ones.

Personalized Lung Cancer Treatment Plans

Each treatment plan is individualized based on the type and stage of lung cancer as well as your overall health. Our lung cancer care team collaborates closely to offer the best protocols and recommend a comprehensive treatment plan tailored specifically for you.

Understanding Your Treatment Options

Having open conversations with your oncologist is crucial. We want to ensure you fully comprehend your lung cancer treatment plan, the expected timeline, and how we will monitor its effectiveness. Our lung cancer specialists at EPCC are committed to helping you feel comfortable and confident in your treatment decisions, working alongside you to develop a plan suited to your unique situation.

Together, we can take meaningful steps toward effectively managing lung cancer and improving your quality of life.

Expert Lung Cancer Treatment, Close to Home

At El Portal Cancer Centers, we understand that a lung cancer diagnosis can be a daunting experience. Fortunately, many treatment options are available, and we are dedicated to tailoring these solutions to meet your individual needs and preferences. Our approach is grounded in the specific type and stage of your lung cancer, ensuring that you receive the most effective care possible.

Chemotherapy for Lung Cancer

Chemotherapy is a cornerstone of cancer treatment that utilizes powerful medications to halt the growth of cancer cells, whether by destroying them or preventing their division. Given that lung cancer often spreads rapidly, chemotherapy plays a critical role in many treatment plans, aimed at eradicating these cells.

The administration of chemotherapy can vary based on your specific situation:

  • Systemic Chemotherapy:When the medication is taken orally or injected into a vein or muscle, it enters the bloodstream, reaching cancer cells throughout the body.
  • Regional Chemotherapy:If injected directly into the spinal column, an organ, or a body cavity like the abdomen, this method targets cancer cells in those localized areas.


Chemotherapy Approaches for Small Cell Lung Cancer (SCLC)

Chemotherapy often forms an integral part of the treatment for SCLC, administered in various ways:

  • Chemoradiation:Combining chemotherapy with radiation therapy is commonly recommended for patients with limited-stage SCLC.
  • Primary Treatment:For some patients with advanced SCLC, chemotherapy may serve as the main treatment option.

Chemotherapy and Radiation Therapies

Chemotherapy for Non-Small Cell Lung Cancer (NSCLC)

For patients with NSCLC, chemotherapy may not always be included in the treatment plan, but it can be appropriate in certain scenarios:

  • Before Surgery:Chemotherapy may be utilized to shrink a tumor, paving the way for less extensive surgical intervention.
  • After Surgery:To eliminate any remaining cancer cells that may not be visible through imaging technology, chemotherapy may follow surgical procedures.
  • For Advanced NSCLC:If the cancer has invaded surrounding areas, chemotherapy combined with radiation can be a critical treatment approach, particularly for tumors that have not yet spread to distant organs.


Radiation Therapy for Lung Cancer

There are two primary types of radiation therapy used in lung cancer treatment:

  • External Radiation Therapy:This method employs a machine to direct radiation toward the cancer from outside the body.
  • Internal Radiation Therapy:This involves placing a radioactive substance directly into or near the tumor through sealed needles, seeds, or catheters. Prophylactic cranial irradiation may also be utilized to prevent the cancer from spreading to the brain.


External beam radiation therapy (EBRT) is the most common form used in lung cancer treatment. This procedure targets high-energy beams at the tumor from outside your body, allowing for a treatment experience similar to receiving an X-ray.

Typically, patients undergo radiation sessions once or twice a day, five days a week, over a period of five to seven weeks, depending on the specific goals and stage of treatment.

Advanced Technologies Treatment Options

Advanced Technologies in External Beam Radiation Therapy

At El Portal Cancer Centers, we utilize cutting-edge external beam radiation therapies to enhance treatment effectiveness while minimizing damage to surrounding healthy tissue. Our techniques include:

  • 3-Dimensional Conformal or Intensity-Modulated Radiation Therapy (IMRT):This advanced system uses specialized equipment to break radiation beams into smaller, adjustable segments, ensuring a precise delivery aimed directly at the tumor while sparing healthy areas.
  • Stereotactic Body Radiation Therapy (SBRT):Using advanced imaging techniques, SBRT targets lung tumors with pinpoint accuracy, delivering high doses of radiation in just one to five treatments, ideal for patients who cannot undergo surgery.

Surgery for Lung Cancer

Small Cell Lung Cancer Surgery

Although less common, surgical options may be considered for small cell lung cancer in select cases where the cancer is localized to one lung and nearby lymph nodes. However, due to the nature of SCLC’s rapid spread, surgical intervention is less frequently utilized.

Non-Small Cell Lung Cancer Surgery

Patients diagnosed with early-stage NSCLC are more likely to undergo surgery to remove tumors. As the cancer advances, surgical options may become more complex due to the potential spread throughout the lung(s).

Post-Surgery Considerations

Even if all visible cancer is removed during surgery, your oncologist may recommend chemotherapy or radiation therapy afterward to target any remaining cancer cells. This follow-up treatment is referred to as adjuvant therapy and is essential for reducing the risk of recurrence.

Lung Cancer Treatments by Stage

Understanding your treatment options based on your lung cancer stage is vital. The approach differs significantly between non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). 

Non-Small Cell Lung Cancer: Tailored Treatments by Stage

Understanding the stages of non-small cell lung cancer (NSCLC) is crucial for determining the most effective treatment approach. Each stage presents unique characteristics that guide treatment decisions.

  • Stage 0 In Stage 0, cancer cells are present on the lining of the airway but have not yet invaded the lung tissue. This early stage is highly treatable, often requiring surgery alone to remove the affected tissue. Additionally, laser therapy may be employed to destroy these cancer cells.
  • Stage 1 Stage 1 NSCLC indicates that the cancer has been detected very early, potentially through a lung cancer screening test. Surgical intervention is typically performed to remove the nodule(s). Following surgery, the removed cells undergo testing to determine whether chemotherapy or immunotherapy is needed based on the specific characteristics of the cancer.
  • Stage 2 For patients in Stage 2, surgery is generally recommended to excise the tumor, followed by chemotherapy to eliminate any remaining cancer cells. Depending on the individual case, immunotherapy and targeted drug therapy may also be introduced during this stage, particularly for patients with certain EGFR gene mutations.
  • Stage 3 At Stage 3, surgical options may still be considered; however, the presence of multiple nodules throughout the lungs can complicate effective surgical intervention. In these cases, alternative treatments such as chemotherapy, radiation therapy, immunotherapy, or targeted therapies may serve as first-line options to manage the disease.
  • Stage 4A In Stage 4, cancer has spread beyond the lungs to another part of the body, such as the brain. However, if the cancer has only metastasized to one additional area, surgery may still be an option to remove the tumor from that location. Radiation therapy may also be utilized to address and destroy any remaining cancer cells.
  • Stage 4B Stage 4B indicates that cancer has often disseminated throughout the body or to various sites. In such cases, biomarker testing becomes a valuable tool to identify specific genetic mutations, guiding the use of targeted therapies aimed at halting cancer growth.

What to Expect on Your Journey

  1. Diagnosis
  • The moment you learn about your diagnosis marks the beginning of your journey as a ‘survivor.’
  • We are committed to guiding you through this phase with education about your cancer and the latest treatment options available.
  • Our compassionate team provides personalized, supportive care to help you understand and navigate your diagnosis.
  1. Treatment
  • Your care team will create an individualized treatment plan tailored to your needs.
  • This may include surgery, chemotherapy, radiation, targeted therapies, or immunotherapy—chosen with your health and goals in mind.
  • During this phase, our goal is to provide expert, compassionate support every step of the way.
  1. Life After Cancer (Survivorship)
  • Post-treatment, the focus shifts to helping you regain your strength and reclaim your life.
  • Our team will work with you to develop a tailored plan supporting your physical, emotional, and mental well-being.
  • We understand that life may change after a diagnosis, and we’re here to help you navigate ongoing challenges, including managing long-term effects and emotional stress.

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Our Commitment to Support and Resources

Emotional and Mental Health Support:  Facing cancer can be overwhelming. We offer counseling services and support groups to help you cope with fear, anxiety, and emotional stress. Mindfulness, stress management, and peer support programs are available to guide you through this healing journey.

Physical Wellness and Rehabilitation: Our team provides physical therapy and rehabilitation services to help restore your strength and mobility. Nutrition counseling and lifestyle guidance can support your recovery and long-term health.

Financial and Practical Assistance: Navigating insurance, treatment costs, and other practical concerns can be challenging. Our financial counselors are here to help you understand your options and connect you with assistance programs.

Educational Resources: Stay informed about your health, treatment options, and advances in cancer care through workshops, written materials, and online resources.

Long-term Monitoring: Regular follow-up appointments and screenings are crucial to detect any recurrence early and to monitor effects of treatment.

How Multiple Myeloma is Diagnosed

Diagnosing Multiple Myeloma typically involves several steps:

  1. Medical History and Physical Examination:
    • Your healthcare provider will start by reviewing your medical history, discussing symptoms you’ve experienced, and conducting a thorough physical examination to check for signs of the disease, such as bone tenderness or swelling.
  2. Blood Tests:
    • Blood tests are essential in diagnosing Multiple Myeloma. Common tests include:
      • Complete Blood Count (CBC): Monitors levels of red blood cells, white blood cells, and platelets.
      • Blood Chemistry Tests: Assess kidney function and other vital parameters.
      • Serum Protein Electrophoresis (SPEP): Identifies abnormal proteins (monoclonal proteins) produced by myeloma cells.
      • Free Light Chain Assay: Measures the levels of free light chains in the blood and can indicate the presence of myeloma.
  1. Urine Tests:
    • A 24-hour urine collection may be performed to check for Bence Jones protein, a type of light chain protein released by myeloma cells.
  2. Bone Marrow Biopsy:
    • A definitive diagnosis often requires a bone marrow biopsy, where a small amount of bone marrow (usually from the hipbone) is extracted and analyzed for abnormal plasma cells.
  3. Imaging Tests:
    • Imaging techniques such as X-rays, CT scans, or MRIs are used to assess bone damage or lesions caused by myeloma. These tests help identify areas of bone weakening or fractures.

Causes & Risk Factors of Multiple Myeloma

While the exact cause of Multiple Myeloma remains unknown, several factors may increase the risk:

  1. Age: The risk of developing Multiple Myeloma increases with age, most commonly affecting individuals over 65.
  2. Gender: Men are more likely to develop Multiple Myeloma than women.
  3. Race: African Americans have a higher incidence of Multiple Myeloma compared to Caucasian populations.
  4. Family History: A family history of Multiple Myeloma or related plasma cell disorders may increase individual risk.
  5. Certain Medical Conditions: Conditions such as monoclonal gammopathy of undetermined significance (MGUS) or other blood disorders can predispose individuals to myeloma.
  6. Exposure to Chemicals: Long-term exposure to certain chemicals, such as benzene, and agricultural chemicals, may contribute to the development of myeloma.

Signs & Symptoms of Multiple Myeloma

Recognizing the signs and symptoms of Multiple Myeloma is crucial for early intervention:

  1. Bone Pain: Persistent pain, particularly in the back, hips, or ribs, may indicate damage to the bones caused by myeloma lesions.
  2. Fatigue: Anemia, caused by reduced red blood cell production, often leads to fatigue and weakness.
  3. Frequent Infections: Compromised immune function due to myeloma can make patients more susceptible to infections.
  4. Unexplained Weight Loss: Patients may experience unexplained weight loss with no changes in their regular diet or physical activity.

Multiple Myeloma Treatment Options

Treatment for Multiple Myeloma is generally tailored to individual patient needs and the disease’s specific characteristics. Here are the primary treatment options:

  1. Chemotherapy: Chemotherapy remains a cornerstone of treatment for Multiple Myeloma. Regimens may include combinations such as:
    • Bortezomib (Velcade):A proteasome inhibitor that blocks protein degradation pathways in cancer cells.
    • Dexamethasone:A corticosteroid used in combination with other drugs to reduce inflammation and manage symptoms.
    • Lenalidomide (Revlimid):An immunomodulatory drug that enhances the immune response against myeloma cells.
  2. Targeted Therapy: Targeted therapies focus specifically on cancerous cells, minimizing harm to normal cells:
    • Monoclonal Antibodies:Medications like daratumumab (Darzalex) are designed to target specific proteins on myeloma cells, leading to their destruction.
    • Carfilzomib (Kyprolis):A newer proteasome inhibitor used in patients with relapsed or refractory myeloma.
  3. Immunotherapy: Immunotherapies use the body’s immune system to fight cancer:
    • Chimeric Antigen Receptor (CAR) T-Cell Therapy:This innovative approach involves modifying a patient’s T-cells to better recognize and attack myeloma cells. It has shown promise for some patients with difficult-to-treat myeloma.
  4. Stem Cell Transplant: For eligible patients, stem cell transplant can provide an opportunity for long-term remission:
    • Autologous Stem Cell Transplant:This involves harvesting the patient’s own stem cells, administering high-dose chemotherapy to eliminate cancer cells, and then reinfusing the healthy stem cells.
  5. Radiation Therapy: Radiation can be used to relieve pain or target specific areas affected by multiple myeloma, particularly in cases of localized disease or bone lesions.
  6. Supportive Care: Supportive care plays a vital role in managing symptoms and improving quality of life. This may include medications for pain relief, management of anemia, hydration support, and nutritional counseling.

Anemia

Anemia is the most prevalent benign blood disorder, impacting more than 3 million Americans, according to the National Heart, Lung, and Blood Institute. Anemia occurs when there is a deficiency of red blood cells or hemoglobin in the blood.

Common Symptoms:

  • Weakness
  • Shortness of breath
  • Dizziness
  • Pale skin


Anemia can particularly affect women during pregnancy or their childbearing years due to increased iron demands.

Causes of Anemia:

  1. Iron Deficiency Anemia: The most common type, usually caused by blood loss from heavy menstrual cycles or gastrointestinal issues, or from inadequate dietary iron. Treatment typically involves iron supplementation, either orally or intravenously.
  2. Aplastic Anemia: A rare condition where the bone marrow fails to produce enough blood cells. Causes may include exposure to toxins, medications, or autoimmune disorders. Diagnosis often requires a bone marrow biopsy. Treatment may include immunosuppressive therapies or bone marrow transplantation.
  3. Hemolytic Anemia: Occurs when red blood cells are destroyed faster than they can be produced. Causes range from infections to autoimmune disorders, with treatment addressing underlying causes and sometimes using corticosteroids.


Anemia Treatment
depends on its cause, severity, and the individual’s overall health. Here are some common treatment options:

  1. Dietary Changes: Increasing intake of iron-rich foods (e.g., red meat, beans, lentils, spinach) and foods high in vitamin B12 and folate (e.g., dairy, eggs, leafy greens).

  2. Iron Supplements: Oral or intravenous iron supplements may be prescribed, especially for iron-deficiency anemia.

  3. Vitamin Supplements: If the anemia is due to vitamin B12 or folate deficiency, supplements or injections may be recommended.

  4. Medications: For anemia related to chronic diseases, medications such as erythropoietin-stimulating agents may be used to stimulate red blood cell production.

  5. Blood Transfusions: In severe cases, a transfusion of red blood cells may be necessary to quickly increase hemoglobin levels.

  6. Managing Underlying Conditions: Treating the underlying cause of anemia, such as chronic kidney disease, can alleviate symptoms.

  7. Bone Marrow Stimulants: In certain cases, treatments that stimulate the bone marrow to produce more red blood cells may be indicated.

It’s essential to consult a healthcare provider for a proper diagnosis and treatment plan tailored to the individual’s specific condition and needs.T

Bleeding Disorders

Bleeding disorders are conditions in which the blood does not clot properly, leading to excessive bleeding. At El Portal Comprehensive Cancer Centers, our experts specialize in treating various bleeding disorders, including hemophilia and von Willebrand disease.

  • Hemophilia: A genetic disorder mainly affecting males, characterized by excessive bleeding from minor injuries. Modern treatments use synthetic concentrated clotting factors administered intravenously, along with vasopressin to manage bleeding.
  • Von Willebrand Disease : An inherited condition caused by a deficiency in a protein essential for blood clotting. Treatment focuses on preventing and managing bleeding episodes, often using synthetic hormones similar to vasopressin.

Treatment options for bleeding disorders like hemophilia and von Willebrand disease (vWD) focus on managing and preventing bleeding episodes. Here are common approaches for each:

Hemophilia:

  1. Factor Replacement Therapy:
    • Prophylactic Treatment: Regular infusions of clotting factor concentrates (Factor VIII for Hemophilia A and Factor IX for Hemophilia B) to prevent bleeding episodes.
    • On-Demand Treatment: Administering clotting factors when a bleeding episode occurs.
  2. Desmopressin (DDAVP):
    • Used for mild cases of Hemophilia A to stimulate the release of stored Factor VIII from blood vessel lining.
  3. Gene Therapy:
    • Investigational treatments aim to provide a functional copy of the missing clotting factor gene, potentially offering a long-term solution.
  4. Supportive Treatments:
    • Pain management and rehabilitation for joint health, along with lifestyle adjustments to prevent injury.


von Willebrand Disease (vWD):

  1. Desmopressin (DDAVP):
    • The first line of treatment for many with type 1 vWD and some with type 2, as it helps increase von Willebrand factor (vWF) and Factor VIII levels in the blood.
  2. Factor Replacement Therapy:
    • Concentrates containing von Willebrand factor and Factor VIII may be used for severe cases or during surgery.
  3. Antifibrinolytic Agents:
    • Medications like tranexamic acid may be used to help prevent bleeding during dental procedures or other situations.
  4. Avoiding Medications That Affect Clotting:
    • Recommendations to avoid aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) that can increase bleeding risk.
  5. Lifestyle and Preventive Measures:
    • Education on avoiding injuries and managing heavy menstrual bleeding in women.


It’s crucial for individuals with bleeding disorders to work closely with a healthcare provider or a specialized hematologist to tailor treatment plans based on their specific needs and to manage their condition effectively.

Blood Clotting Disorders

Treatment options for blood clotting disorders aim to prevent clots from forming, manage existing clots, and reduce the risk of complications. Here are some common approaches based on different types of clotting disorders:

1. Anticoagulant Medications:

– Warfarin (Coumadin): A vitamin K antagonist used to prevent the formation of new clots and to keep existing clots from growing.

– Direct Oral Anticoagulants (DOACs): Medications such as apixaban (Eliquis), rivaroxaban (Xarelto), and dabigatran (Pradaxa) that directly inhibit specific clotting factors.

2. Antiplatelet Medications:

– Aspirin: Often used to prevent clot formation in arteries, particularly in individuals with a history of heart attacks or stroke.

– Clopidogrel (Plavix): Another antiplatelet medication that may be used alone or in combination with aspirin.

3. Thrombolytics:

– Clot Busters: Medications like alteplase (Activase) are used in emergency situations to dissolve large clots quickly, such as those causing strokes or pulmonary embolisms.

4. Compression Therapy:

– Compression Stockings: Used to improve blood flow and reduce swelling in individuals with venous thromboembolism (VTE) or chronic venous insufficiency.

5. Surgery:

– Thrombectomy: Surgical removal of a blood clot may be necessary in severe cases.

– Placement of Inferior Vena Cava (IVC) Filters: A filter may be placed in the IVC to catch clots that may travel from the legs to the lungs, particularly in patients with recurrent clots.

6. Lifestyle and Preventive Measures:

– Dietary Changes: Monitoring vitamin K intake (for patients on warfarin) and maintaining a balanced diet.

– Regular Exercise: Encouraging activity that enhances blood flow, while ensuring safety to avoid injury.

– Hydration: Staying well-hydrated to help maintain proper blood viscosity.

7. Management of Underlying Conditions:

Treating conditions that contribute to clotting disorders, such as atrial fibrillation, hormonal imbalances, or certain types of cancer.

Genetic Counseling:

For hereditary clotting disorders, genetic counseling may be beneficial for affected individuals and their families to understand risks and management strategies.

It’s essential for individuals with blood clotting disorders to work closely with a healthcare provider to develop a tailored treatment plan and to monitor their condition effectively. Regular follow-up and education about the disorder are also crucial parts of effective management.

Myelodysplastic Syndromes (MDS)

Myelodysplastic syndromes represent a group of disorders where the bone marrow fails to produce healthy blood cells, leading to insufficient white blood cells, red blood cells, and platelets. Patients with MDS may experience:

  • Increased risk of infections due to low white blood cell counts.
  • Fatigue and shortness of breath from anemia.
  • Excessive bleeding due to low platelet levels.


Treatment options
may include blood transfusions, medications to stimulate blood cell production, or immune-suppressive therapies.

Dr. Alireza Mahmoudieh, M.D.

Dr. Mahmoudieh has been a vital member of El Portal Comprehensive Cancer Centers since 2008, bringing over a decade of dedicated experience to patient care. Before joining our team, he served as the Director of the Prostate Brachytherapy Program at Kaiser Permanente in Sacramento and Roseville, demonstrating his leadership in advanced cancer treatments.

He earned his medical degree from the Albert Szent-Györgyi School of Medicine in Szeged, Hungary, in 1996. With a strong interest in treating head, neck, and breast cancers, Dr. Mahmoudieh specializes in cutting-edge techniques such as Image-Guided Radiation Therapy (IGRT) and Intensity-Modulated Radiation Therapy (IMRT). His expertise extends to treating cancers of the head and neck, lung, gastrointestinal tract, and prostate.

A committed professional, Dr. Mahmoudieh is a member of the American Society for Therapeutic Radiology and Oncology (ASTRO), reflecting his engagement with ongoing developments in cancer treatment and research. His compassionate approach and advanced skill set ensure that each patient receives personalized, state-of-the-art care.

Outside of his professional life, Dr. Mahmoudieh enjoys traveling with his son and daughter, as well as reading and playing racquetball, embracing a balanced and active lifestyle. His dedication to both his patients and his personal passions makes him a trusted partner in your journey toward health.

Dr. Osman Elhanafy, Ph.D

Dr. Elhanafy is a highly respected Associate Professor of Medical Physics and serves as the Chief Medical Physicist at El Portal Comprehensive Cancer Centers since July 2013. He earned his Ph.D. in Medical Physics from the University of Wisconsin, Madison—where he began his foundational training and completed his thesis—in 2013, building on his initial joining of the university in 1999.

 With specialized training in advanced radiation oncology techniques—such as Intensity-Modulated Radiation Therapy (IMRT), High-Dose Rate Brachytherapy (HDR), Stereotactic Radiosurgery (SRS), Total Body Irradiation (TBI), Quality Assurance, and Radiobiology—Dr. Elhanafy brings a wealth of expertise to patient care. His dedication to the field is evident through numerous published research articles, as well as awards recognizing his leadership in organizing conferences, training sessions, lectures, and workshops.

Beyond his impressive credentials, Dr. Elhanafy is deeply committed to advancing medical physics and ensuring the best possible outcomes for his patients. His compassionate approach, combined with his extensive knowledge, makes him a trusted partner in your cancer care journey.

Outside of his professional pursuits, he values spending quality time with his family, reflecting his genuine care and balance in life.

Dr. Harish Ahuja, M.D.

Dr. Ahuja is a distinguished, board-certified Medical Oncologist with extensive training in medical hematology. He has refined his expertise at renowned institutions such as Tata Memorial Hospital, UCLA School of Medicine, and Roswell Park, under the mentorship of esteemed hematologists including Dr. S.H. Advani, Dr. Michael Caligiuri, and Dr. M.J. Cline.

With over 25 years of experience in both hematology and oncology, Dr. Ahuja offers a deep well of knowledge and a compassionate approach to patient care at El Portal Cancer Center. His dedication to advancing the field is reflected through active membership in prestigious professional organizations, including the American Society of Hematology, the American Society of Clinical Oncology, the European Society of Medical Oncology, and the Indian Society of Medical and Pediatric Oncology.

A passionate researcher, Dr. Ahuja has contributed significantly to ongoing scientific advancements—serving on the NRG Breast Committee and the Rare Subtype Committee, and acting as Principal Investigator for the “CROWN” NCORP study. His commitment to clinical excellence and groundbreaking research underscores his dedication to improving outcomes for his patients.

Outside of his professional pursuits, Dr. Ahuja values spending quality time with his family, and enjoys hiking and traveling, embracing life outside the clinic with the same dedication he brings to his medical practice. His compassionate nature and extensive experience make him a trusted partner in your cancer care journey.

Dr. Sidney Crain, M.D.

Dr. Crain is a highly experienced and board-certified Medical Oncologist and Hematologist with over 45 years of dedicated service in the medical field. Throughout his distinguished career, he has established himself as a leading expert in the diagnosis, treatment, and prevention of various cancers and blood disorders.

He earned his medical degree from the University of Illinois College of Medicine in 1977 and is actively affiliated with esteemed institutions, including Adventist Health St. Helena. Dr. Crain’s extensive experience spans a broad range of conditions, including small intestine and colorectal cancers, breast cancer, prostate cancer, anemia, leukemia, and lymphoma.

Beyond his clinical expertise, Dr. Crain is deeply committed to advancing medical research and improving patient care. His approach to treatment is rooted in compassion and a thorough understanding of complex medical conditions, ensuring each patient receives personalized, comprehensive care.

Recognized for his empathetic nature and unwavering dedication, Dr. Crain strives to achieve the best possible outcomes for his patients and foster a trusting, supportive environment. His lifelong commitment to the fields of oncology and hematology reflects his passion for making a meaningful difference in his patients’ lives.

Michael Kangas

Michael Kangas serves as the Director of Oncology and Diagnostic Imaging, where he spearheads initiatives that enhance revenue, profitability, productivity, and patient satisfaction within an underserved area. His leadership is instrumental in developing and guiding a highly skilled team of healthcare professionals across multiple clinics, providing comprehensive cancer care and diagnostic imaging services utilizing the most advanced technology. Michael’s commitment is rooted in delivering personalized, high-quality care to each patient, ensuring they receive the support they need throughout their journey.

With extensive expertise in Health Information Management, Electronic Medical Records (EMR), Radiation Therapy, Radiation Oncology, Clinical Operations, Healthcare Compliance, and Regulatory Standards, Michael ensures that all services meet the highest industry standards. He also focuses on monitoring performance, healthcare marketing, and supervisory skills to foster a collaborative, efficient, and patient-centered environment.

In addition to his clinical leadership, Michael actively volunteers with the Merced Cancer Society Foundation as its Executive Director. In this role, he oversees key operational and administrative functions to advance the foundation’s mission of positively impacting residents in the Central Valley. His efforts include community outreach, organizing fundraising events, and leading initiatives to expand the foundation’s support and resources for local cancer patients.

Michael’s dedication to improving healthcare and strengthening community ties highlights his unwavering commitment to healing, hope, and making a meaningful difference in the lives of those he serves.

Paul Mosher

Paul I. Mosher is a highly accomplished business professional with extensive experience in healthcare management, medical device sales, and community service. Currently, he proudly serves as the Physician Liaison and Business Development Coordinator at El Portal Comprehensive Cancer Center. In this role, Paul collaborates closely with our dedicated medical team to facilitate patient-centered care, foster strong relationships with our physicians, and support the center’s mission of providing the highest quality cancer treatment.

With expertise in business development, leadership, relationship management, and healthcare technology, Paul is a dedicated and effective communicator committed to exceptional service and compassionate support. His collaborative approach helps ensure that patients receive not only cutting-edge treatment but also personalized care rooted in trust and understanding. Additionally, Paul brings ten years of non-profit experience to our board of directors, furthering his devotion to community health and service.

Paul holds a Bachelor of Business in Business Marketing from Boise State University. He is actively involved in his community, volunteering with various Merced non-profits and churches. Outside of work, Paul enjoys spending quality time with his family and playing golf whenever he can.

How Does Radiation Therapy Work?

During radiation therapy, a team led by a radiation oncologist—a specialist in this treatment—will carefully plan and supervise your treatment. Each session typically involves directing high-energy radiation toward the cancer cells using specialized equipment. This targeted exposure fractures the DNA within the cancer cells, making it difficult for them to grow and multiply. While healthy surrounding cells may also be exposed to some radiation, most can recover and continue functioning normally, whereas cancer cells generally cannot.

At El Portal Comprehensive Cancer Centers, we utilize the latest and most advanced radiation technologies to minimize exposure to healthy cells. Our accredited equipment undergoes daily checks to ensure the highest level of precision in treatment.

Types of Radiation Therapy

There are two main categories of radiation therapy:

External Beam Radiation Therapy

This method delivers radiation from a machine outside the body, directing beams specifically at the cancer site. The equipment does not physically contact the body and can be adjusted to deliver radiation from multiple angles. Treatment typically occurs five days a week for a duration ranging from 1 to 10 weeks.

Technologies may include:

  • TrueBeam Radiotherapy:Offers advanced options tailored to your specific anatomy and cancer type.
  • Image-guided Radiation Therapy (IGRT):Uses imaging (such as CT or ultrasound) to accurately direct radiation.
  • Intensity-modulated Radiation Therapy (IMRT):Shapes radiation beams around tumors while sparing surrounding healthy organs.
  • Stereotactic Radiosurgery (SRS):A non-invasive approach treating irregularly shaped tumors, particularly in the brain.
  • Stereotactic Body Radiation Therapy (SBRT):Similar to SRS, but designed for tumors outside the skull.
  • Hypofractionated Radiation Therapy:A specialized technique for breast cancer treatment, depending on individual patient factors.


Internal Radiation Therapy

Internal radiation therapy, or brachytherapy, involves placing radioactive material directly inside or near the tumor. This may include various implants such as pellets, seeds, or tubes, which are inserted using minimally invasive methods.

At El Portal Comprehensive Cancer Centers, we offer:

  • High-Dose Rate (HDR) Brachytherapy:Often utilized for uterine or cervical cancers, this approach involves placing radioactive material for short durations multiple times.
  • Selective Internal Radiation Therapy (SIRT):An innovative, non-surgical procedure for liver tumors, delivered via tiny radioactive beads inserted directly into blood vessels leading to the tumor.

How Does My Doctor Determined If Radiation Therapy Is Right for Me?

After a cancer diagnosis, you will likely be referred to a cancer specialist, such as a surgical oncologist or medical oncologist. Your treatment plan, which may include radiation therapy, is tailored uniquely based on:

  • Type and grade of cancer
  • Size and location of the tumor
  • Sensitivity of surrounding tissue
  • Genetic components
  • Family history
  • Age, overall health, and medical background
  • Personal treatment goals and preferences


Your doctor will also consider whether you have previously received radiation to that area, as each body part has a safe lifetime dose of radiation. The decision to proceed with radiation for recurrence depends on the location of the tumor, cancer type, and past radiation exposure.

Radiation therapy may be recommended as a standalone treatment or in conjunction with surgeries, chemotherapy, or immunotherapy. At El Portal Comprehensive Cancer Centers, we typically can schedule your first appointment within two days of your referral.

Choosing El Portal Comprehensive Cancer Centers for Radiation Therapy

Radiation therapy demands a high degree of skill, precision, and experience. Selecting a provider with state-of-the-art technology and strict protocols ensuring equipment accuracy is essential.

At El Portal Comprehensive Cancer Centers, we have been delivering high-quality radiation therapy for patients across California for over 15 years. Our board-certified radiation oncologists bring expertise and compassion to your care.

Key factors to consider include:

  • Technology:Choose a center equipped with the most advanced equipment for optimal treatment.
  • Experience:Our dedicated team ensures patients receive knowledgeable and compassionate care.
  • Affordability:As the largest community-based cancer center, we strive to provide services in a cost-effective

Skin Cancer Symptoms

The most critical warning sign of skin cancer is the appearance of a new spot on the skin or changes in an existing spot that seem abnormal. Following the A B C D E guidelines can help you identify the common signs of skin cancer:

  • Asymmetry:One half of a mole (or birthmark) does not match the other half.
  • Border:Edges are irregular, ragged, notched, or blurred.
  • Color:The color is uneven, often featuring different shades of brown or black, along with patches of pink, red, white, or blue.
  • Diameter:The spot is larger than 6 millimeters across (about the size of a pencil eraser).
  • Evolving:The mole is changing in size, shape, color, or elevation. 

Skin Cancer Diagnosis

Skin cancer is typically identified first by a healthcare professional during an examination of an unusual area on the skin. However, determining whether it is cancerous requires removal and subsequent testing, known as a biopsy. This is the only reliable method to confirm a skin cancer diagnosis.

You may have your biopsy performed in a dermatologist’s office or as an outpatient procedure in a hospital or clinic, depending on the size and location of the abnormal area. Local anesthesia is usually administered to ensure your comfort.

There are four common types of skin biopsies:

  • Punch Biopsy:A sharp, hollow tool is used to remove a circle of tissue from the abnormal area.
  • Incisional Biopsy:A scalpel is employed to remove a portion of the growth.
  • Excisional Biopsy:The entire growth and some surrounding tissue are removed with a scalpel.
  • Shave Biopsy:A thin, sharp blade is used to shave off the abnormal growth.


If there is a possibility of melanoma, dermatologists will generally avoid simply shaving or cauterizing the growth. Instead, an excisional biopsy will be performed, or if the growth is too large, a tissue sample will be collected.

Staging Skin Cancer and Melanoma

Upon receiving a biopsy confirmation of skin cancer, you will be referred to a specialized oncologist for further evaluation and care. Understanding the extent, or stage, of your cancer is crucial, whether you have melanoma or nonmelanoma skin cancer. Staging involves a meticulous assessment to determine how thick the tumor is and whether it has metastasized to other parts of the body. If the tumor is particularly thick, your doctor may recommend chest x-rays, blood tests, and imaging scans of the liver, bones, and brain.

Knowing the stage of your cancer enables your oncologist to:

  • Assess the seriousness of your cancer and your chances for survival
  • Formulate the most effective treatment plan for your unique situation
  • Identify clinical trials that may present additional treatment options


In some cases, your oncologist may need to examine your lymph nodes to accurately stage the cancer. Surgical procedures may be part of the treatment plan to remove cancerous lymph nodes, which can aid in managing the disease.

Staging Criteria
Staging is based on several key factors:

  • The size of the tumor
  • How deeply it has penetrated below the surface of the skin
  • Whether it has spread to nearby lymph nodes or other organs


Oncologists utilize Roman numerals I through IV to designate the cancer stage. Stage I indicates small tumors that are confined to their original site, while Stage IV signifies advanced cancer that has spread to distant sites in the body.



Nonmelanoma Skin Cancer Staging
The stages of nonmelanoma skin cancer are as follows:

  • Stage 0: The cancer is localized to the top layer of skin, classified as carcinoma in situ.
  • Stage I: The tumor measures 2 centimeters (approximately three-quarters of an inch) or smaller.
  • Stage II: The tumor exceeds 2 centimeters in diameter.
  • Stage III: The cancer has spread beyond the skin to underlying tissues such as cartilage, muscle, or bone, or to nearby lymph nodes, but not to distant locations.
  • Stage IV: The cancer has metastasized to other areas in the body.


Melanoma Staging
The staging for melanoma specifically is defined as follows:

  • Stage 0: Melanoma cells are confined to the outer layer of skin (epidermis) and have not invaded deeper tissues.
  • Stage I: In Stage I, the melanoma is considered thin:
    • The tumor is no thicker than 1 millimeter (1/25 inch) and may show signs of ulceration (a scraped appearance).
    • Alternatively, the tumor measures between 1 and 2 millimeters thick without ulceration, and melanoma cells have not spread to nearby lymph nodes.
  • Stage II: At this stage, the tumor is at least 1 millimeter thick:
    • It may be between 1 and 2 millimeters thick and present with ulceration.
    • Alternatively, the tumor may be greater than 2 millimeters thick, potentially with ulceration, but has not yet spread to nearby lymph nodes.
  • Stage III: This indicates that melanoma has spread to nearby lymph nodes or to tissues just outside the original tumor without affecting the lymph nodes.
  • Stage IV: At this advanced stage, melanoma cells have metastasized to other organs, lymph nodes, or distant skin areas.
  • Recurrent: Recurrent disease indicates that cancer has returned after treatment, either in the original site or in a new location within the body.

Skin Cancer Treatment Based on Type

There are various approaches to treating skin cancer, and your oncologist will work closely with you to determine the most effective combination of therapies based on the stage of cancer and your overall health. We at El Portal Comprehensive Cancer Centers are dedicated to providing you with comprehensive care tailored to your needs, ensuring you receive the support, guidance, and treatment necessary for your journey toward recovery.



Nonmelanoma Skin Cancer Treatments

In some cases, the entire nonmelanoma skin cancer may be removed during the biopsy, which means no further treatment is necessary. However, if additional treatment is required, your doctor will outline the available options.

There are six primary types of nonmelanoma skin cancer treatments, which may be used individually or in combination:

  1. Surgery
  2. Chemotherapy
  3. Photodynamic therapy
  4. Radiation therapy
  5. Biologic therapy
  6. Targeted therapy


Melanoma Skin Cancer Treatments

Melanoma treatment encompasses nearly all the same options as nonmelanoma skin cancer, with the exception of photodynamic therapy.



Skin Cancer Treatment Options

Your oncologist can provide detailed explanations of the following surgical techniques:

  • Wide-Local Excision (WLE): This common approach involves numbing the area and surgically removing the cancer along with a margin of surrounding healthy skin. The margin is examined microscopically to ensure all cancer cells have been excised, and the required margin size will depend on the tumor’s dimensions. In some cases, nearby lymph nodes may also be removed.
  • Mohs Surgery: This technique is particularly beneficial for skin cancer treatment. The surgeon numbs the area and removes thin layers of the tumor, examining each layer under a microscope for cancer cells. The process continues until no cancerous cells are detected, ensuring complete tumor removal while preserving as much healthy tissue as possible.
  • Electrodesiccation and Curettage: This method is ideal for small basal cell skin cancers. The doctor numbs the area, removes the cancer using a curette (a spoon-shaped surgical instrument), and then employs an electric current to control bleeding and eliminate any remaining cancer cells. This procedure tends to be quick and straightforward.
  • Cryosurgery: This option is suitable for patients who may not tolerate other surgical methods. Cryosurgery employs extreme cold, typically generated from liquid nitrogen, to treat early-stage or very thin skin cancer lesions. While effective, this approach may cause swelling and could damage nerves in the area, leading to temporary loss of sensation.
  • Laser Surgery: This technique involves using a focused beam of light to target and destroy cancer cells. It is primarily utilized for superficial growths confined to the outer layer of skin.
  • Skin Grafting: Occasionally, grafts are necessary to cover openings left by surgical removal. In this procedure, the surgeon numbs the area and removes a patch of healthy skin from another part of your body, such as the thigh, to cover the excised area. It is important to provide special care to the graft site during the healing process.
  • Lymphadenectomy: This surgical procedure may be employed in the case of melanoma, wherein lymph nodes are removed for evaluation. The removed tissue is examined under a microscope for cancer cells.
  • Sentinel Lymph Node Biopsy: During this procedure, the sentinel lymph node—the first node likely to receive cancer spread from the tumor—is surgically removed. A radioactive substance and/or blue dye is injected near the tumor site to track the flow to the lymph nodes. If no cancer cells are found in the sentinel node, additional nodes may not need to be excised, making this a useful technique within melanoma treatment plans.

Treatment and Surviving

During Treatment

Receiving a cancer diagnosis can evoke feelings of shock, fear, anger, or uncertainty. The stress of treatment side effects, hospital visits, and lifestyle changes can lead to anxiety and depression. It is normal to experience a wide range of emotions during this time. Maintaining open communication with your healthcare team about your emotional well-being is essential. Psychological support or counseling can provide tools to manage anxiety, depressive symptoms, and emotional distress.

Surviving Cancer

While completing treatment brings relief, many survivors face ongoing emotional challenges such as fear of recurrence, adapting to physical changes, or reintegrating into daily life. Feelings of vulnerability, grief, or identity shifts are common. Building a support network, engaging in self-care, and participating in survivorship programs can foster resilience and emotional strength. Remember, healing is not only physical but also mental and emotional.

Support and Resources

Supporting mental health throughout the cancer journey involves accessing appropriate resources:

  • Counseling and Therapy: Licensed mental health professionals, including psychologists and social workers, specialize in addressing cancer-related emotional issues. Sessions can offer coping strategies, emotional processing, and support for anxiety or depression.
  • Support Groups: Connecting with others who have similar experiences provides comfort, shared knowledge, and a sense of community. Many organizations offer in-person and virtual support groups for patients and caregivers.
  • Mind-Body Techniques: Practices such as meditation, yoga, relaxation exercises, or journaling can reduce stress and promote emotional balance.
  • Educational Resources: Learning about common emotional reactions to cancer can normalize your experience and provide helpful coping tips. Many cancer centers and organizations offer educational materials or workshops.
  • Emergency Support: If you experience severe depression, thoughts of self-harm, or suicidal feelings, seek immediate help by contacting emergency services or going to the nearest emergency room.


Where to Get Help:

  • Talk to your healthcare team about mental health concerns; they can refer you to mental health specialists experienced in oncology.
  • Contact local mental health clinics or community organizations offering counseling services.
  • Utilize national resources like the American Cancer Society’s Reach To Recovery program or the National Alliance on Mental Illness (NAMI).

Infusion Therapy - Conditions Treated

Infusions are used to treat a wide range of medical conditions, including:

  • Cancer: Chemotherapy agents, targeted therapies, and immunotherapies are often administered via infusion to treat various cancers such as breast, lung, and leukemia.
  • Autoimmune Disorders: Conditions like rheumatoid arthritis, lupus, and multiple sclerosis may be treated with biological agents delivered through infusions to help regulate the immune system.
  • Infections: Severe infections might require antibiotics delivered through infusion for immediate and effective treatment.
  • Nutritional Support: Patients unable to eat or absorb nutrients through the gastrointestinal tract may receive nutritional solutions (Total Parenteral Nutrition, TPN) via infusion.
  • Pain Management: For chronic pain conditions, infusions of medications such as opioids or analgesics may provide relief.
  • Hydration and Electrolyte Replacement: IV fluids are commonly used for rehydration in patients with severe dehydration or electrolyte imbalances.

Risk Factors for Infusion Therapy

While infusion therapy is generally safe, certain factors may increase the risk of complications, including:

  • Allergies:Some patients may have allergic reactions to medications being infused.
  • Infection Risk:The insertion of IV lines can lead to infections if not performed under sterile conditions.
  • Pre-existing Conditions:Patients with compromised immune systems, heart conditions, or kidney issues may face additional risks.
  • Substance Interactions:Patients should disclose all medications, supplements, and herbal products they are taking, as interactions can occur.


Timing of Treatments:
The timing of infusion treatments varies based on the condition being treated:

  • Cancer Patients: Infusion schedules can be based on specific chemotherapy regimens, often occurring every few weeks or as prescribed by an oncologist.
  • Autoimmune Disorders: Infusions may be scheduled monthly or as part of a broader treatment plan based on symptoms and disease activity.
  • Acute Conditions: Infusions for infections or severe hydration may occur as needed, often in a hospital setting.

Side Effects of Infusion Therapy

Side effects of infusion therapy can vary depending on the type of medication and individual patient factors. Common side effects include:

  • Infusion Reactions:Fever, chills, or rashes occurring during or shortly after the infusion.
  • Nausea and Vomiting:Particularly common with chemotherapy agents.
  • Fatigue:Many patients experience tiredness following infusion sessions.
  • Infections:Risks associated with the use of IV lines.
  • Local Reactions: Bruising, swelling, or inflammation at the injection site.

Success Rates of Infusion Therapy

The success rate of infusion therapy depends on several factors, including:

  • Type of Condition: Certain cancer treatments administered via infusion can have high cure rates, especially when applied at early stages.
  • Individual Response: How a patient responds to the specific medication influences effectiveness.
  • Comprehensive Treatment Plan: Optimizing infusion therapy as part of a broader treatment strategy (including surgery, radiotherapy, etc.) can enhance success rates.


For example:

  • Chemotherapy: May lead to significant tumor shrinkage or remission in many cancer patients.
  • Biologics for Autoimmunity: Often result in substantial improvements in symptoms and quality of life for patients with autoimmune diseases.

Accepted Insurance Carriers

AUTHORIZATION REQUIRED: 

  • Alignment Health Plan    
  • AllCare IPA Merced (HMO/NO DERM)  
  • ALLIANCE (CCAH)
  • Anthem MediCAL Managed Care Prog.  
  • Brand New Day-Universal Care, Inc.- Medicare 
  • Calviva Health 
  • Community Care IPA
  • California Forensic Medical Group, Inc  
  • Health Plan of San Joaquin HMO
  • Kova Healthcare, Inc. IPA  
  • Imperial Health Medical
  • MediCAL  
  • Central Valley Medical Providers IPA
  • Sequoia Health IPA 
  • United Healthcare (AARP)
  • Sante Community Physicians  
  • Tricare TriWest Healthare
  • Alliance  
  • Western Growers Assurance Trust  
  • Central Valley Pace County Medical Services Program 
  • Esperanza IPA- Medicare HMO
  • Choice Program
  • HealthNet CA- First Health Hill Physicians 
  • Humana LaSalle Network Management IPA  
  • Meritage Medical Network
  • Seven Corners 


NO AUTHORIZATION REQUIRED: 

  • Aetna
  • Anthem
  • Blue Cross of CA  
  • Blue Shield of CA
  • Medicare 
  • UMR ACPN Network-America’s Choice PN  
  • First Health Network-Cofinity Galaxy Health Network
  • HealthSmart 
  • CIGNA
  • Anthem ACA Plans- Pathway EPO, PPO 
  • BS of CA Promise Health Plan
  • Medicare
  • Railroad Multiplan/PHCS  
  • NaphCare NX Health Network LLC d/b/a Valenz Access 
  • Provider Network of America (PNOA)
  • Wellcare
  • WelbeHealth 

What You Need to Do

  • Verify benefits, plan limits, referral, and pre-authorization requirements before your appointment.
  • Bring your insurance card(s).
  • Notify us of any insurance or personal information changes immediately.
  • Understand your financial responsibility for co-pays, deductibles, and non-covered services.

How EPCC Assists You

  • We verify and review your benefits.
  • We help obtain necessary referrals and authorizations.
  • We provide cost estimates.
  • We inform you about financial assistance options.
  • We bill your primary and, if authorized, secondary insurance.
  • For Medicare patients, supervising physician info will be included on your claims.
  • Our Financial Counselors can provide resources for you to help navigate obtaining traditional insurance coverage 

Your Responsibilities

  • Present your current insurance card at each visit.
  • Keep us updated on insurance info.
  • Pay co-pays at the time of service.
  • Cover any balances remaining after insurance payments.

Support for Your Physical Well-Being

Caring for someone with cancer can make maintaining your own health seem difficult. To effectively care for your loved one, it’s vital to schedule time for your own medical appointments and self-care routines. Prioritizing your health ensures you have the strength and energy to continue providing support. Incorporate self-care practices such as maintaining a balanced diet, getting adequate sleep, engaging in regular physical activity, and practicing relaxation techniques like deep breathing or meditation.

There are resources to help you stay physically active and connected to the world around you. If you need help finding services in your area, contact an EPCC social worker.

Emotional Support

The emotional toll of caregiving can lead to feelings of isolation and exhaustion. The following resources can help nurture your emotional well-being and provide strategies for maintaining balance while caring for your loved one.

Our social workers are available to offer counseling and connect you with local support services. To speak with a licensed social worker, contact your nearest EPCC location during business hours.

Important: In case of an emergency, do not leave a message—call 911 directly.

Social Support and Practical Help

Connecting with others and carving out time for yourself can be difficult. Getting assistance with everyday tasks can free up energy and reduce stress.

  • Reducing Stress and Anxiety: Share your feelings with family and friends so they understand your needs. Consider designating one or two people as primary contacts to communicate important updates or coordinate help.
  • Organizing Support: Organizing support for cancer patients can make a significant difference in their quality of life and treatment experience. Here are some ideas:
  • Create a Care Calendar or Schedule: Use tools like Lotsa Helping Hands or a shared online calendar to coordinate tasks such as meal preparation, transportation, errands, and childcare.
  • Designate Support Roles: Assign specific responsibilities to friends or family members—e.g., one person manages appointments, another handles meals, and someone else provides emotional support.
  • Use Digital Platforms: Set up a private CaringBridge site or Facebook group for updates, sharing needs, and organizing volunteer efforts.
  • Meal Train: Organize a meal delivery schedule through services like MealTrain.com to ensure consistent nutritious meals.
  • Transportation Assistance: Coordinate rides to treatment appointments through community programs, local volunteer driver services, or rideshare apps.
  • Host Support Groups: Establish or join local or virtual support groups for patients and caregivers to share experiences and advice.
  • Organize Practical Help: Arrange for cleaning services, home repairs, or pet care through local providers or community resources.
  • Spiritual and Emotional Support: Connect with local chaplain services, spiritual care providers, or mental health counselors who can offer guidance and comfort.
  • Fundraising and Resources: Set up crowdfunding campaigns or organize community fundraising events to support medical expenses or related needs.
  • Encourage Self-Care and Reflection: Support the patient in incorporating activities like meditation, journaling, or nature walks into their routine, and facilitate access to these resources.


Implementing even a few of these strategies can greatly ease the burden on patients and caregivers, fostering a supportive community around their treatment and recovery.

Resources in Your Area:

  • Meal Delivery: Meals on Wheels — check their website for local providers.
  • Transportation: Local transportation services in the Central Valley, or the American Cancer Society Road to Recovery (800-227-2345).
  • Cleaning Services:
    Modesto:
    MaidPro Modesto — Professional cleaning services including residential and light commercial cleaning.
    Sweet Home Cleaning — Offers regular and deep cleaning options for homes.

    Merced:
    Maid in Merced — House cleaning services with flexible scheduling.
    Merced Cleaning Service — Residential cleaning, move-in/move-out cleaning, and special deep cleaning.

    Manteca:
    Manteca Cleaning Service — Residential and commercial cleaning, including carpet and upholstery cleaning.
    Simply Clean Manteca — Home cleaning services tailored to your needs.


Please note that it’s advisable to verify current availability, reviews, and insurance coverage before hiring any service.

  • Home Care Support: Consult your medical team for referrals suitable to your needs, with local providers available in Modesto, Merced, and Manteca.

Caring for Your Spirit

Spirituality can mean different things to each person, often related to finding purpose and connection in life. As a caregiver, taking time for reflection and nurturing your spirit is essential but can be overlooked.

Resources and practices such as meditation, guided visualization, journaling, spending time in nature, or connecting with a spiritual care provider can be helpful.

Connecting with Spiritual Support:
Start by contacting your local hospital’s pastoral care or chaplain services. They can connect you with a non-denominational chaplain or spiritual counselor who can offer support and guidance aligned with your beliefs or preferences.

If you need additional assistance or specific resources tailored to your area, please contact a social worker at your EPCC location.

What to Bring to Your First Visit

Please try to bring the following:

  • Insurance card(s) and referral if required
  • Driver’s license or other photo ID
  • Prescription card
  • Completed new patient forms (if not done online)
  • Relevant medical records, including test results, scans, and reports (some providers may send these directly to us)
  • Contact info for your primary care or referring doctor so we can coordinate your care


Please avoid wearing perfumes, colognes, or heavily scented lotions, as many patients are sensitive to strong smells in the clinic.

Follow-Up Appointments

Before you leave, you can schedule any future appointments needed. These might include:
  • Blood tests
  • Chemotherapy or radiation treatments
  • Follow-up visits with your doctor
  • Additional imaging tests

Our team is always available to help you understand your treatment plan and to answer any questions. During these visits, your care team will review your diagnosis—what type and stage of cancer you have—and discuss your treatment goals. Some cancers may be treated with the aim of curing the disease, while others focus on slowing growth or reducing symptoms.

Insurance & Payment Information

Our friendly and knowledgeable billing team is experienced in helping you understand your insurance benefits, including Medicaid and Medicare coverage for cancer treatments. They can discuss what your insurance may cover and help arrange payment plans for any out-of-pocket costs.

Please note that co-payments may be required at the time of your visit, especially for office visits or treatments like chemotherapy.

We accept cash, checks, and major credit cards—including Visa, MasterCard, Discover, and American Express—to make payments convenient for you.

Questions and Topics

Here are some additional important questions and topics that patients often want to know about during their first appointment:

Understanding Your Diagnosis

  • What does my specific diagnosis mean?
  • How advanced is my cancer, and what stage is it in?
  • What are the possible causes or risk factors?


Treatment Options and Outcomes

  • What treatments are available for my type of cancer?
  • What are the potential benefits and side effects of each option?
  • How effective are these treatments?
  • What is the recommended plan, and why?


Treatment Timeline

  • How long will my treatment last?
  • How often will I need to come in for treatment or appointments?
  • What can I expect during each phase of treatment?


Impact on Daily Life

  • How might treatment affect my daily activities, work, or home life?
  • Are there lifestyle changes I should consider?
  • What kind of support or assistance is available for daily needs?


Managing Side Effects

  • What side effects should I watch for?
  • How can I manage or minimize side effects?
  • When should I contact my care team about specific symptoms?


Support and Resources

  • Are counseling, support groups, or peer resources available?
  • Can I access nutritional guidance or physical therapy?
  • How do I find emotional support during this journey?


Second Opinions

  • Is it advisable to get a second opinion?
  • How can I arrange for one if I choose?


Financial and Practical Concerns

  • What will my treatment cost?
  • Are there financial assistance programs?
  • How do I navigate insurance coverage or billing questions?


Long-term Follow-up

  • What happens after initial treatment?
  • How will I be monitored for recurrence?
  • What signs or symptoms should I watch for in the future?


Personal Questions and Concerns

  • How do I talk to my family about my diagnosis?
  • How can I maintain my mental health and well-being?


Encouraging open dialogue and reassuring patients that asking questions is normal and important can help them feel more comfortable, supported, and engaged in their care.