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Your Strength. Our Knowledge and Experience.

When faced with a cancer diagnosis, the journey ahead is profoundly influenced by the support of the best doctors, options, and support team who work with you.

Mother with her two daughters
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We see you. All of you.

At El Portal Comprehensive Cancer Centers (EPCC), you will benefit from a dedicated team of doctors, nurses, and treatment professionals united by one common goal: an unwavering commitment to your health and well-being. 

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Your fight is personal for us.

We will deliver personalized, world-class care infused with compassion and kindness. Here, you can trust that you will receive cutting-edge treatment along with the highest quality of care.

Compassionate care is premiere at El Portal Cancer Center in the Central Valley of California
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Choose El Portal Comprehensive Cancer Centers as your trusted partner in this journey.

We are the largest multidisciplinary practice in Central California dedicated solely to providing care for patients with cancer and diseases of the blood.

Infusion Services

Madera Infusion Center prioritizes your health with a commitment to providing excellent care. The first step towards better health is just a drip away, ensuring that you receive the support and treatment you need to enhance your well-being. Learn More information about Infusion Therapy.

Hematology/Oncology

Chemotherapy, Targeted Therapy, Immunotherapy, Iron (Infed, Venofer, Injectafer,  Feraheme, Monoferric), Therapeautic Phlebotomy

Neurology

IVIG, Tysabri, Solu-Medrol, Ocrevus, Leqembi,  Briumvi, Kisunla

IV Infusion/Injectable

Normal Saline (IV Fluids), IV Antibiotics, Prolia, Reclast, Evenity, Dupixent, & Xolair

Rheumatology

Rituxan, Actemra, & Orencia

Gastroenterology

Remicade, Entyvio, Stelera, Cimzia, & Skyryzi

Wellness

Vitamin C infusions, Myers Cocktail infusions,   Glutathione infusions, NAD+ Booster Infusions,  Inflammation and Detoxifying Treatments, Immune  Boosting Drip Treatments, Skin Rejuvenation   Infusions, as well as B12, Lipo-B, and NAD+   Injections

What our patients have to say...

april B.
21:29 22 May 25
I feel fortunate to have been referred to Dr.M as my hematologist. He's been very attentive, thorough, and caring. He is a great Doctor who cares about his patients. Thank you so much Dr. M for caring, as well as to his staff who've been professional and kind also.
Stella Z.
15:40 19 May 25
Amazing place, front desk and doctors are friendly.
Neveah
18:55 01 May 25
i love it here the ladies here are so nice and have a gentle hand when it comes to the needle. i feel comfortable and unjudged here and enjoy the time i spend here getting to talk to everyone.
Jaimie C.
22:43 30 Apr 25
Love every single one of the girls who work in the infusion room. They do such a great job and always make sure we are comfortable and taken care of.
Natasha G.
16:32 24 Apr 25
I can’t say enough great things about this place! From the moment I walked in, the staff made me feel more like family than a patient. Everyone is incredibly friendly, professional, and truly goes above and beyond to make sure you're comfortable. They explain every step of the process in detail, which really helps put your mind at ease.

The iron infusion room is spotless—super clean and sanitized, which I really appreciated. Danica and her amazing team are simply the best. Their care, compassion, and warmth made such a difference during my treatment. Once I’m done, I know I’ll truly miss them.

Thank you to the entire staff for making this experience as smooth and comforting as possible. Highly recommend!
Patricia L.
21:35 21 Apr 25
Thank you Isabel MA for your amazing help, best communication and treatment I received here much lovely service here
Mychelle C.
19:00 26 Mar 25
Danika is awesome!!! She always makes sure to make sure I am as comfortable as possible!! The girls are all amazing!!

Share Your Journey with Us!

At El Portal Comprehensive Cancer Centers (EPCC), we believe that every story matters. Your experiences, struggles, and victories can inspire others who are navigating their own cancer journeys. By sharing your story, you not only help build a supportive community but also empower others to find hope and strength.

Working together to explore treatment options and to create a personalized plan based on your diagnosis and lifestyle.